Medicina-Pregrado
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Item Frecuencia y asociación entre helicobacter pylori, metaplasia, displasia y neoplasia gástricas en el Laboratorio H&E de la ciudad de Cuenca en el periodo julio 2020- diciembre 2021(Universidad de Cuenca. Facultad de Ciencias Médicas, 2025-11-18) Espinoza Lituma, Juan David; Chicaiza Capón, David Mateo; González Domínguez, Esteban HoracioBackground: Helicobacter pylori (H. pylori) can colonize the gastric mucosa and affects more than half of the world's population, with a higher prevalence in developing countries. The World Health Organization (WHO) recognizes it as a Type I carcinogen due to its association with gastric adenocarcinoma. High rates of infection and gastric neoplasms are recorded in our setting, although recent local studies are limited. Objectives: To determine the frequency and association of H. pylori infection, metaplasia, dysplasia, and gastric neoplasia in patients evaluated at the H&E laboratory in the city of Cuenca between July 2020 and December 2021. Methods: An analytical, observational, retrospective, cross-sectional study. A total of 653 histopathological reports were analyzed to evaluate the frequency and association between variables using analytical statistical analysis. Results: The prevalence of H. pylori was 62.6%. Intestinal metaplasia reached 45.9%, dysplasia 22%, and neoplasia 2.8%, with poorly differentiated adenocarcinoma and the intestinal subtype predominating. Metaplasia (χ2=143,3; p=0,001; OR adjusted=0,420; IC95%: 0,201–0,879) and dysplasia (χ2=38,1; p=0,001; OR crude=0,332; IC95%: 0,203–0,544) were more frequent in H. pylori-negative subjects. Glandular atrophy showed a positive gradient association with metaplasia (OR=4,1– 7,2) y dysplasia (OR=7,7–21,2). Neoplasia was not associated with H. pylori in the crude analysis (χ2=0,735; p=0,391), but an independent association emerged after adjustment (OR=202,4; IC95%: 2,71–15.129; p=0,016). Furthermore, incidentally, a considerable frequency (83.5%) of patients with data suggestive of autoimmune gastritis was found.Item Prevalencia de riesgo alto de fibrosis hepática mediante FIB-4 y factores asociados en pacientes con sobrepeso, obesidad y diabetes del grupo industrial GRAIMAN. Cuenca. 2025(Universidad de Cuenca. Facultad de Ciencias Médicas, 2025-10-23) Siavichay Cabrera, Gina Estefania; Ureña Morocho, Juana Brigith; Jiménez Encalada, Marcia GabrielaSteatohepatitis associated with metabolic dysfunction (MASH) has increased in global incidence in recent decades. It is linked to obesity, diabetes, and the development of liver fibrosis and cirrhosis. The objective of this study was to determine the prevalence of high risk for liver fibrosis using the FIB-4 index and to identify associated factors in patients with overweight, obesity, and diabetes from the Graiman Industrial Group, Cuenca, 2025. A quantitative, analytical, cross-sectional study was conducted with 517 workers from the Graiman Industrial Group in Cuenca, in 2025. A worker database was used, with prior authorization obtained through the signing of informed consent sent via email. Additional data were collected, and the liver fibrosis risk index was calculated using the following equation: FIB-4 score = [Age (years) × AST (U/L)] / [Platelets (10⁹/L) × √ALT (U/L)]. The data obtained were analyzed using SPSS version 26. Both descriptive and analytical statistics were applied. The results showed a predominance of male participants (88.4%), with a mean age of 40.18 ± 9.22 years. 69.4% were overweight, and 30.6% had some degree of obesity. According to the FIB-4 index, 9.1% were at high risk for liver fibrosis. Although higher risk was observed among workers with HDL ≤45 mg/dL, triglycerides ≥150 mg/dL, and increased waist circumference, none of these associations reached statistical significance (p > 0.05). However, a BMI ≥27 kg/m² showed a trend toward statistical significance (p = 0.082), suggesting a possible clinical association.Item Hábitos alimentarios y estado nutricional en adultos mayores con diagnóstico de diabetes mellitus tipo 2 atendidos en consulta externa de Geriatría del Hospital de Especialidades José Carrasco Arteaga durante el período enero-marzo de 2025(Universidad de Cuenca. Facultad de Ciencias Médicas, 2025-10-13) Maita Loja, Bryan Alexander; Orbe Gualancañay, Leidy Esthefania; Larriva Villareal, Diana KatherineObjective: To assess the eating habits and nutritional status of older adults diagnosed with type 2 diabetes mellitus, who were seen at the geriatrics outpatient services of José Carrasco Arteaga Specialty Hospital from January to March 2025. Methods and materials: This is a quantitative cross-sectional analytical study applying MNA and ECAAM. The sample comprised 80 older adults from the geriatrics outpatient service. PSPP 2.0 was used to process and analyze information. Statistical measures included frequencies, percentages, and the Chi-square test, with a significance level of 0.05 and a 95% confidence interval. Results: Out of 80 respondents, 60% were older adults, 51.2% were men, 58.8% had a partner, and 63.7% lived in urban areas. The prevalence of poor diet quality was 70%. 38.8% were obese, and 33.8% were overweight. The prevalence of malnutrition was 42.5%, and the risk of malnutrition was 23.8%.100 % of people showed malnutrition and 47.36% of those at risk had poor diet quality. A statistically significant association was found between eating habits and nutritional status. Conclusions: Over half of the older adults with T2DM had poor diet quality, along with significant levels of malnutrition and risk of malnutrition. A statistically significant association was found between eating habits and nutritional status in this population.Item Prevalencia de depresión, ansiedad, estrés académico y factores de riesgo asociados en los estudiantes de la Carrera de Odontología de la Universidad de Cuenca, 2025(Universidad de Cuenca. Facultad de Ciencias Médicas, 2025-10-03) Camas Ortiz, Cristhian Joel; Andrade Salazar, Cristhian Hernán; Morocho Malla, Manuel IsmaelBackground: The study of depression, anxiety, and academic stress in dental students is essential due to their impact on psychological well-being and academic performance. Objective: To determine the prevalence of depression, anxiety, academic stress, and associated risk factors among students of the Dentistry Program at the University of Cuenca, 2025. Methodology: An observational, analytical, and cross-sectional study with a random sample of 94 dental students. A sociodemographic questionnaire and the DASS-21 scale (α > 0.7) were administered. Measures of central tendency and frequencies were used; the association was analyzed with the chi-square test (p < 0.05); the analysis was performed using SPSS version 26. Results: Of the students surveyed, 60.6% were female, with a mean age of 18.7 years (SD = 1.11); 52.1% were 18 years old, 97.9% were single, and 90.4% lived in urban areas. Regarding mental health, a prevalence of anxiety was 13.8%, depression 6.4%, and stress 1.1%. Being 18 to 19 years old was a protective factor against anxiety (OR = 0.179; p = 0.003), while being 20 to 25 years old represented a risk factor (OR = 7.424; p = 0.001). No significant associations were found between anxiety and the variables sex, marital status, or place of residence. Conclusion: Anxiety was the most prevalent disorder among students, with age being a significantly associated factor in its onset.Item Prevalencia y factores asociados a disfunción sexual femenina en estudiantes de la Facultad de Ciencias Médicas de la Universidad de Cuenca, 2024(Universidad de Cuenca, 2025-10-01) Coraisaca Cordero, María Verónica; Chamba Murillo, Pamela Isabel; Vanegas Coveña, Diana PatriciaBackground: According to studies, sexual dysfunction affects people of all ages and is correlated with lower satisfaction. These types of problems are not always addressed in young people. Research has shown that sexual dysfunction is related to sociodemographic variables. Objectives: To determine the prevalence and factors associated with female sexual dysfunction in students at the Faculty of Medical Sciences of the University of Cuenca, 2024. Method: quantitative, analytical, cross-sectional study with a sample of 275 female university students over the age of 18 from the Faculty of Medical Sciences at the University of Cuenca, enrolled in 2024. The study sample will be calculated proportionally to the students enrolled in each degree program. Surveys based on the “Female Sexual Function Index” (FSFI) will be used, based on the prevalence of 67.2% from a study conducted at the University of Azuay. SPSS version 27.0 will be used for data analysis; for quantitative variables, central tendency statistics (mean) and dispersion statistics (standard deviation) will be applied, while for qualitative variables, frequencies and percentages will be used. In the study of associated factors, statistical tests Will be used according to the behavior of the data obtained. Results: we expect to determine the prevalence and factors associated with female sexual dysfunction in students at the Faculty of Medical Sciences of the University of Cuenca, 2024.Item Calidad de vida y depresión en adultos mayores del Centro Geriátrico “Hogar Cristo Rey” de la ciudad de Cuenca, periodo diciembre 2024 - mayo 2025(Universidad de Cuenca, 2025-10-01) Carchipulla Pucha, Jenny Marina; Escandón Barnuevo, Giannela Alejandra; Parra Parra, Jorge LeonidasBackground: Quality of life refers to the overall well-being of individuals and encompasses physical, psychological, and social aspects. It can be influenced by many factors, such as depression which, according to the WHO, affects more than 264 million people worldwide. In older adults, its prevalence is high due to factors such as social isolation, the loss of loved ones, and chronic illnesses. Understanding quality of life allows it to be related to the diagnosis and treatment of various pathologies in this group. Objective: To determine the quality of life and depression in older adults at the “Hogar Cristo Rey” Geriatric Center, in the city of Cuenca, during the period December 2024 – May 2025. Method: A descriptive, cross-sectional study. The population consisted of 120 older adults, with a sample of 101 (4% margin of error and 95% confidence level). The WHOQOL-BREF and the Geriatric Depression Scale by Yesavage were applied. Data were processed in Excel and analyzed using SPSS version 28.0 (trial version). Quantitative variables were reported using mean and standard deviation; qualitative variables were presented using frequencies and percentages. Results: 90.0% presented a moderate quality of life, 7.5% very low, and 2.5% high. Regarding emotional state, 42.5% were in the normal range, 33.3% had mild depression, 14.2% moderate, and 10.0% severe. An inverse relationship between both variables was observed. Conclusions: Although most participants had a moderate quality of life, more than half showed some degree of depression, highlighting the need for comprehensive emotional care in institutional settings.Item Adherencia al tratamiento en la enfermedad renal crónica y sus factores asociados en pacientes que acuden a consulta externa en el Hospital de Especialidades José Carrasco Arteaga en el periodo enero-marzo 2025(Universidad de Cuenca, 2025-09-26) Cárdenas Coello, Mariela de los Ángeles; Naula Pesantez, Katherine Lissbeth; Ordóñez Chacha, Pablo RobertoBackground: Chronic Kidney Disease (CKD) is a prevalent and highly impactful health pathology globally, primarily due to its progression to advanced stages requiring major treatments like renal replacement therapy. Adherence to treatment is critical for mitigating CKD aggravation and improving patients' quality of life. However, multiple factors can hinder this adherence, ranging from socioeconomic conditions to psychological and clinical barriers. Objective: To determine the level of treatment adherence in CDK and its associated factors in patients attending outpatient consultations at the José Carrasco Arteaga Specialty Hospital during the January-March 2025 period. Method: A cross-sectional analytical study was conducted with a sample of 333 CKD patients who received care at HJCA during the specified period. The ARMS-e and MOS questionnaires were used to analyze adherence and associated factors, such as social support. Results: The average age of the surveyed patients was 53.76 years. Characterization of the population revealed that most were men (54.7%) and resided in urban areas (76.6%). The predominant marital status was married (55.9%), and the most frequent educational level was secondary (34.8%). It was found that 309 patients perceived having good social support (global, emotional, instrumental, interactive, and affective). However, 69.7% of those with low emotional support were non-adherent, and 71.4% with low instrumental support were also non-adherent.Item Conocimientos, actitudes y prácticas asociadas al almacenamiento y eliminación de desechos farmacéuticos domiciliarios en empleados de la empresa pública municipal ETAPA EP, 2025(Universidad de Cuenca, 2025-09-25) Abril Ortiz, Pedro José; González Ordóñez, Karol JannethIntroduction: The proper management of household pharmaceutical waste represents a significant challenge for public health and the environment. This study addresses the knowledge, attitudes and practices associated with the storage and disposal of these wastes in employees of the municipal public company ETAPA EP. Objective: To describe the current knowledge, attitudes and practices of the employees of the municipal public company ETAPA EP in relation to the storage and disposal of household pharmaceutical waste. Methods: A cross-sectional descriptive study was conducted in a population of 304 employees, to whom a digital survey validated by experts was applied. The data obtained were analyzed in the SPSS V26 Statistical program. Results: 58.1% of the population did not identify the different types of pharmaceutical waste; 20.5% recognized all the risks associated with poor management of this waste; 81.3% and 84.5% (respectively) recognized not knowing how to correctly store and dispose of their medicines; 91.4% and 91.8% (respectively) said they had not received information on the correct way to dispose of their medicines from pharmaceutical dispensers; Practices: 73.0% store medicines in their homes (mainly analgesics, vitaminssupplements and antibiotics), 30.7% dispose of them in a differentiated manner, as well as 50% have a person in charge of these at home. Conclusions: Most participants have deficient knowledge and inadequate practices regarding the management of their household pharmaceutical waste, as well as its risks; however, they exhibit a positive attitude towards the importance of good management, the application of community regulations and programs.Item Prevalencia del consumo de alcohol en una población recicladora y su asociación con factores socioeconómicos, Cuenca 2023(2025-09-24) Portilla Alvarez, Gladys Maribel; Toro Valencia, Tamia Doménica; Gómez Ayora, Andrea XimenaThe waste-picking population, often invisible in society, faces limitations ranging from limited access to basic services to precarious working conditions. These circumstances affect their physical and mental health, making it necessary to analyze factors such as alcohol consumption, which influences their well-being (1). Excessive alcohol consumption is one of the main public health problems worldwide. The World Health Organization recognizes it as a priority, promoting the reduction of harmful habits to mitigate its effects on society and individual health (2). In this context, the objective was to analyze the relationship between alcohol consumption and socioeconomic factors in the waste-picking population through a cross-sectional, observational, and analytical study. The research was based on the primary study "Health, work, and public policies with a gender perspective and approach. The case of women waste pickers in three urban environments of Cuenca, La Libertad, and Macas. Ecuador, 2023-2024." The findings showed that the prevalence of alcohol consumption among recyclers in Cuenca during 2023 was 69.7%, a figure higher than hypothesized. Significant associations were also identified with socioeconomic variables such as educational level (p=0.0000027), monthly income (p=0.0238), and occupation (p=0.0285). The high prevalence reflects the impact of precarious socioeconomic conditions, especially low educational attainment and insufficient income. Therefore, interventions that reduce stigmatization, improve access to health services, and promote labor formalization are key strategies.Item Epidemiología de los adultos con diagnóstico de fibrosis quística atendidos en el área de neumología del Hospital Vicente Corral Moscoso durante el periodo enero-diciembre 2024(Universidad de Cuenca, 2025-09-23) Peñaloza Tinoco, Arianna Mayerli; Larco Duche, Valentina Michelle; Uyaguari Ali, Juan PabloBackground: cystic fibrosis (CF) is an autosomal recessive genetic disease caused by mutations in the CFTR gene (ΔF508 being the most common). It is a multi-organ disease whose life expectancy has increased in recent years. In Ecuador, studies on the adult population are scarce, and there is a lack of information about this group. Objective: to describe the epidemiology of adults diagnosed with cystic fibrosis who were treated in the Pulmonology Department of the Vicente Corral Moscoso Hospital during the period January–December 2024. Methodology: observational, descriptive, retrospective, and cross-sectional study involving 13 adult patients. Data were collected through the review of medical records (MEDISYS system) and the department’s database. The data were analyzed using descriptive statistics (Epi Info™ 7.2.6 and Excel 2019). Results: the average age was 28.85 years (53,80% female), with a predominance of urban origin (76,90%) and the majority coming from Azuay (61,50%). The diagnosis was made at an average age of 16.85 years, mainly through sweat testing (84,60% positive). All patients presented with bronchiectasis (76,90% with total bilateral involvement), and 76,90% showed spirometric obstruction. The most frequent bacterial colonization was by Pseudomonas aeruginosa (53,85%) and Staphylococcus aureus (46,15%). A total of 38,46% required hospitalization due to exacerbations. Conclusions: adults with CF in this region exhibit late diagnosis, a high burden of pulmonary disease, and frequent colonization by different pathogens. These findings highlight the need to strengthen early diagnosis, access to genetic testing, and comprehensive management of this understudied population.Item Adherencia al tamizaje cérvico uterino en docentes mujeres de la Facultad de Ciencias Médicas de la Universidad de Cuenca, en el periodo 2025(Universidad de Cuenca, 2025-09-18) Alarcón Serrano, Kerly Jomara; Gutama Gutama, Erika Gabriela; Vega Crespo, Bernardo JoséBackground: Around the world, cervical cancer is the fourth leading cause of death from gynecological cancer. In Ecuador, even with prevention and early detection programs, morbimortality rates are high. High-risk human papillomavirus (HPV) infection is the main etiological factor, especially in women who do not have regular access to health services. Likewise, even health professionals face barriers such as lack of time, ignorance or fear of the procedure, affecting their adherence. Objective: To determine the adherence to cervical uterine cancer screening among female teachers of the Faculty of Medical Sciences of the University of Cuenca. Methods: A descriptive-transversal study which encompasses a sample of 118 female professors who work in the faculty of Medical Sciences. Results: The average age was 41.26 years. Sixty-four.4% were married and 59.8% had a master's degree. Adherence to cervical uterine screening was 80.5%, with 55.1% having been tested annually. 95.8% were aware of the risk of HPV infection, but 14.6% did not know the result of their cytology. Conclusion: Adherence to screening was high, but gaps persisted in the follow-up of results, which shows the need to reinforce post-screening control, even among teaching staff.Item Evaluación del riesgo de diabetes tipo 2, prediabetes y factores asociados utilizando el cuestionario CANRISK en pacientes atendidos en el Hospital Municipal de la Mujer y el Niño, Cuenca, durante el periodo enero-marzo de 2025(Universidad de Cuenca, 2025-09-15) Rea Ochoa, Mateo Francisco; Villalba Paladines, Jamileth Stefania; Ordónez Chacha, Pablo RobertoBackground: Type 2 diabetes mellitus (T2DM) is a chronic disease that affects quality of life and places a burden on healthcare systems. Tools such as the CANRISK questionnaire help identify risk, enabling early interventions. Objective: To evaluate the risk of developing T2DM, prediabetes, and associated factors in patients attended at the Municipal Hospital for Women and Children of Cuenca using the CANRISK questionnaire. Methodology: An analytical study was conducted on 270 patients (95% confidence interval, 5% margin of error). The CANRISK questionnaire was applied to determine the 10-year risk of developing T2DM and prediabetes. Additionally, a form was used to collect sociodemographic data. Statistical analysis was performed using SPSS v15, employing frequencies, percentages, and the Chi-square test (p<0.05). Results: Seventy percent of participants were women, with a mean age of 38.42 ± 14.98 years. A significant association was found between T2DM risk and variables such as older age, low educational level, high body mass index, abdominal obesity, and hypertension (p<0.001). No association was observed with sex, physical activity, diet, smoking, alcohol, or time since the last medical check-up. Conclusion: CANRISK is a simple tool with high sensitivity (89.6%) for identifying T2DM risk, although its specificity is limited (45.9%). Its application in Ecuador is limited; however, the results are consistent with international studies, showing statistically significant associations with variables such as hypertension, obesity, and age.Item Adherencia al tratamiento farmacológico y no farmacológico en pacientes con hipertensión arterial en el Centro de Salud Carlos Elizalde, Cuenca 2024(Universidad de Cuenca, 2025-09-08) Siguencia Cantos, Kely Jazmin; Ureña Cajamarca, Daniela Alexandra; Roldán Fernández, José VicenteBackground: Hypertension is a problem with worldwide repercussion being the main risk factor for cardiovascular morbimortality, for its management it requires pharmacological and nonpharmacological treatment, lack of adherence to it increases the risk of relapse, appearance of complications and delays in recovery. Objective: to determine the degree of adherence to pharmacological and non-pharmacological treatment in patients with arterial hypertension in the Carlos Elizalde health center, Cuenca 2024. Methodology: quantitative cross-sectional analytical study, carried out in 255 hypertensive patients at the Carlos Elizalde health center in Cuenca, in whom the level of adherence to pharmacological and nonpharmacological treatment was determined. The measures used to present the results were frequencies, percentage, arithmetic mean, standard deviation, Chi-square, Student's t-test, prevalence ratio, and the Kolmogorov-Smirnov test. Results: 62.0% were female, 52.2% were aged up to 64 years, 60.4% had completed primary school, 58.6% were housewives, 57.6% were married, 60.4% had a socioeconomic level of stratum IV, 62.8% had a disease evolution time of 10 years or less, 38.8% were non-adherent, 62.0% had a good lifestyle, and 46.3% experienced high threat. Conclusions: women are more adherent to treatment than men, the variables that showed a statistically significant relationship with non-adherence to pharmacological and non-pharmacological treatment were the type of farming occupation and the lifestyle: danger, low or regular.Item Frecuencia de complicaciones postoperatorias en hernioplastias abdominales en el Hospital de Especialidades José Carrasco Arteaga. Febrero - mayo 2024. Cuenca(Universidad de Cuenca, 2025-09-02) Marín Torres, Karen Marcela; Pasaca Jumbo, Steffi Mariel; Tenezaca Tacuri, Ángel HipólitoBackground: abdominal hernias are a frequent pathology worldwide, and their treatment accounts for a large percentage of all scheduled surgeries. The objective of the study was to estimate the frequency of postoperative complications in abdominal hernias in a level three hospital, the specialty hospital José Carrasco Arteaga, during the period from February to May, 2024. Methods: Descriptive study. Data set: 52 patients. A data collection form was used to obtain data including sociodemographic information, co-morbidities, clinical characteristics and complications. The data was processed using SPSS version 26.0 and tables were produced which summarize the analysis. Results: The average age of the study population was 60 years (DS ±14,298); 50% were older adults; 59.6% were men; 50% were overweight; 15.4% had diabetes mellitus and 23.1% had hypertension. Of all the cases, 52.5% were inguinal hernias, the Lichtenstein technique was used in 53.8%, the TEP technique was used in 9.6%, and 100% of hernioplasties used synthetic mesh. The prevalence of postoperative complications was 80.8%, with pain being the most common, both immediately post-operatively and as a late complication, at 44.1% and 8.5% respectively. Other complications included surgical site infection, seroma, wound dehiscence, and urinary retention, which all occurred at a rate of 5.1%. Conclusion: the prevalence of complications after hernioplasty was high overall relative to other studies, but the rates were comparable for some specific complications.Item Frecuencia de diagnóstico de tuberculosis en los pacientes atendidos en el HVCM durante el periodo pre pandemia, pandemia y post pandemia de COVID- 19. Enero 2018 - octubre 2023. Cuenca, Ecuador(Universidad de Cuenca, 2025-08-29) Ortiz Verdugo, María Emilia; Ortega Sinchi, Mauro Sebastián; Aguirre Bermeo, Hernán MarceloBackground: Tuberculosis (TB) corresponds to a highly prevalent infectious disease in Latin America, caused by the bacterium Mycobacterium tuberculosis. COVID-19 corresponds to an infection caused by the SARS-CoV-2 virus. Both pathologies share pulmonary affinity in their clinical presentation, airborne transmission, and risk factors for development such as overcrowding. Objectives: To describe the frequency of tuberculosis diagnosis in the pre pandemic, pandemic, and post pandemic periods in patients treated at the Hospital Vicente Corral Moscoso from January 2018 to October 2023. Methods: An anonymized database of patients diagnosed with tuberculosis during the periods January 2018 to October 2023 was analyzed. Chi-square was calculated to determine the association of variables, with a significance level of 0.05. Results: Two divisions of the periods were made according to the definition of pandemic by the WHO and the definition of pandemic by HVCM. According to the pandemic period defined by the Vicente Corral Moscoso Hospital, there is an increase in TB cases after the pandemic; this increase shows a statistically significant relationship with male sex compared to female (66.9% vs. 33.1%, respectively), p=0.03. These results were not evidenced in the division according to the WHO definition. Conclusions: in the local definition of pandemic by HVCM, the results are similar to those reported globally and regionally,showing a decrease in the diagnosis of tuberculosis cases during the pandemic and subsequently an increase in TB detection post-pandemic.Item Características y evolución clínica de los pacientes con diagnóstico de COVID- 19 ingresados en la Unidad de Cuidados Intensivos del Hospital Vicente Corral Moscoso, marzo 2020 - octubre 2021, Cuenca, Ecuador(Universidad de Cuenca, 2025-08-28) Cambizaca Loja, Belén Estefanía; Chiriapo Pulgarín, Luz Marianela; Aguirre Bermeo, Hernán MarceloIntroduction: The pandemic provoked by the SARS-COV2 virus resulted in a great challenge to health-care systems around the world. Additionally, information about the clinical features and evolution of the resultant disease were lacking in different countries including our own. Objective: To establish the features and clinical outcome in COVID-19 patients admitted to the ICU at the “Hospital Vicente Corral Moscoso” during March 2020 to October 2021 in Cuenca, Ecuador. Methodology and Resources/Tools: Descriptive, Cross-Sectional, and Retrospective Research. Demographic variables, clinical outcomes, and patients’ evolution were registered during their admission to ICU from march 2020 to october 2021. Results: 61,4% of the patients were men. Symptoms started to appear within 8±4 days. The most frequent comorbidity was hypertension. The most common symptoms and signs were dyspnea and tachypnea. During their admission, all patients presented hypoxemia. Therefore, they required breathing support. The most common technique used for this purpose was oxygen therapy. Hospitalization overall time was 13 days. Mortality was 36,2% average.Conclusions: The results gathered about clinical features were similar to those described regionally and globally. The mortality rate in our study is underneath the rates described in similar research within our region, but slightly superior to developed countries. This fact illustrates the differences in the health-care system, response capacity, and socio-economic resources.Item Frecuencia de depresión y su relación con la capacidad funcional en pacientes con artritis reumatoide atendidos en el Hospital José Carrasco Arteaga de la ciudad de Cuenca, periodo: enero – mayo 2024(Universidad de Cuenca, 2025-08-28) Hernandez Abad, Angel Eduardo; González Cartuche, Rosa Mercedes; Feicán Alvarado, Elsa AstridIntroduction: Rheumatoid arthritis is a chronic autoimmune disease present globally with a prevalence of 0.5-1%, it is directly and indirectly related to countless pathologies. Depression is the most common mental health disorder associated with rheumatoid arthritis, being twice as frequent in this group of patients than in the general population. The patient's functional capacity is affected by the chronic degenerative polyarticular involvement of the disease in close relationship with depression, causing the loss of the individual's physical function with limitations in the personal and work environment. Objectives: To determine the frequency of depression and its relationship with functional capacity in patients with rheumatoid arthritis treated at the José Carrasco Arteaga Hospital in the city of Cuenca, period: January-May 2024. Methods: Observational analytical cross-sectional study, using a sample of 185 patients. The Health Assessment Questionnaire was used to assess functional capacity and the Patient Health Questionnaire to assess depression. Results: According to the results of the PHQ-9, 15.5% of patients presented severe depression, and 22.2% presented a mild degree of depression. Regarding the HAQ, 48.45% presented moderate disability, while 10.82% presented severe disability. There is a high and positive relationship between the variables studied (r = 0.69).Item Riesgo cardiovascular y factores asociados en pacientes de 20 a 65 años que acuden al Centro de Especialidades Médicas de la Universidad de Cuenca, 2024(Universidad de Cuenca, 2025-08-28) Quichimbo Contreras, Karla Anabel; Campoverde Romero, Melissa Lizbeth; Álvarez Serrano, Marlene ElizabethBackground: cardiovascular risk (CVR) estimation is a useful tool for the management of preventive measures on risk factors. Objective: to determine the CVR and its associated factors in patients aged 20 to 65 years who attend the Centro de Especialidades Médicas de la Universidad de Cuenca during the period February to June 2024. Methodology: it is a descriptive cross-analytical study, carried out in the Centro de Especialidades Médicas de la Universidad de Cuenca, with 196 participants selected by stratified convenience sampling. The data were processed by the SPSS 25 tool and presented in baseline tables for descriptive statistics; the Chi Square and 95% Prevalence Ratio test was used to relate the variables of the study with the level of CVR by Framingham heart study. Results: of the total participants, 54.1% were men and 89.3% were over 30 years old. 87.2% of respondents had a low CVR, 11,7% had a moderate CVR and 1.1% with a high CVR. A higher prevalence of moderatehigh CVR was found in patients aged ≥ 60 years PR 3.17 (95% CI: 3.17-6.65), systolic hypertension PR 8.08 (95% CI: 4.61-14.16), hypertensive medication PR: 5.63 (95% CI: 2.62- 12.09), diabetes mellitus PR: 6.94 (95% CI: 3.61-13.34) and tobacco consumption PR: 3.22 (95% CI: 1.55-6.66). Conclusions: CVR presents a significant association with age over 60 years, HBP medication, systolic hypertension, presence of DM type 2 and tobacco consumption; evidencing a huge prevalence of low cardiovascular risk.Item Prevalencia de hipertensión arterial primaria y factores asociados en pacientes mayores de 30 años atendidos en el Centro de Especialidades Médicas de la Universidad de Cuenca, Ecuador. Enero – junio 2023(Universidad de Cuenca, 2025-08-28) Idrovo Bernal, Andrea Fernanda; Izquierdo Flores, Camilo José; Álvarez Serrano, Marlene ElizabethBackground: High blood pressure affects more than 30% of the adult population around the world, being one of the pathologies with the most negative long-term consequences, especially when it comes to cardiovascular diseases, which is why its control and prevention is important. Objective: Identify the prevalence of primary arterial hypertension and its associated factors in patients. from the age of 18 years treated at the Medical Specialties Center of the University of Cuenca, Ecuador. January - June 2023. Methodology: Descriptive cross-sectional - analytical study, carried out at the Center for Medical Specialties of the University of Cuenca. The observational method was used based on the retrospective review of an anonymized database. The data were processed using SPSS V 26 and are presented in baseline tables, as well as contingency tables between prevalence of primary hypertension and associated factors. Results: The average age was 49.76 ± 20,084. The prevalence of primary arterial hypertension was 18.14%. The associated factors were: age ≥ 55 years (PR 8.25 95% CI 4.49-15.20), obesity (PR 2.31 95% CI 1.54-3.46), dyslipidemia (PR 2.14 95% CI 1.37-3.32) and sedentary lifestyle (PR 3.76 CI 95 % 2.09-6.76). All statistically significant (p<0.05). Conclusions: Primary arterial hypertension was associated with age, obesity, dyslipidemia and sedentary lifestyle.Item Tumor miofibroblástico inflamatorio de comportamiento incierto. Reporte de un caso(Universidad de Cuenca, 2025-08-27) Zhizhpón Mora, Karol Nathaly; Vazconez Siguencia, Ibeth Tatiana; Bravo Muñoz, Marx ItaloInflammatory myofibroblastic tumor (IMT) is an extremely rare tumor, considered benign, but with an intermediate biological behavior. Objective: describe an inflammatory myofibroblastic tumor clinical case diagnosed in SOLCA cancer institute, Cuenca-Ecuador, for subsequent analysis and literature research. Case Report: a 76-year-old woman, non-smoker, with a history of breast cancer, presented with acute onset dyspnea and productive cough. The chest X-ray revealed bilateral lung nodules, raising suspicion of metastasis. Three fine needle aspiration biopsies were performed without obtaining a precise diagnosis. Subsequently, a limited thoracotomy was performed for lung biopsy, the histology of which was consistent with IMT. Conclusion: this pathology should be suspected in the presence of lung masses with nonspecific clinical and imaging characteristics. Its diagnosis is established through surgical excision and histopathology. The expression of the ALK gene in these tumors influences the prognosis and treatment, so a therapeutic option is ALK inhibitors, which have shown effectiveness in advanced cases. An early diagnosis and long-term follow-up are crucial due to the risk of recurrence.