Tumor miofibroblástico inflamatorio de comportamiento incierto. Reporte de un caso

Abstract

Inflammatory myofibroblastic tumor (IMT) is an extremely rare tumor, considered benign, but with an intermediate biological behavior. Objective: describe an inflammatory myofibroblastic tumor clinical case diagnosed in SOLCA cancer institute, Cuenca-Ecuador, for subsequent analysis and literature research. Case Report: a 76-year-old woman, non-smoker, with a history of breast cancer, presented with acute onset dyspnea and productive cough. The chest X-ray revealed bilateral lung nodules, raising suspicion of metastasis. Three fine needle aspiration biopsies were performed without obtaining a precise diagnosis. Subsequently, a limited thoracotomy was performed for lung biopsy, the histology of which was consistent with IMT. Conclusion: this pathology should be suspected in the presence of lung masses with nonspecific clinical and imaging characteristics. Its diagnosis is established through surgical excision and histopathology. The expression of the ALK gene in these tumors influences the prognosis and treatment, so a therapeutic option is ALK inhibitors, which have shown effectiveness in advanced cases. An early diagnosis and long-term follow-up are crucial due to the risk of recurrence.