Concentración de ceramidas séricas en vacas lecheras de la provincia del Azuay en lactancia temprana, media y tardía

Abstract

The objective of this study was to determine the serum ceramide concentration in Holstein dairy cows in the province of Azuay during the different stages of lactation: early, middle, and late. The study also aimed to evaluate the relationship between these levels and parity and milk production. This quantitative, observational, cross-sectional, and analytical study involved collecting blood samples from 78 Holstein cattle divided into three homogeneous groups based on their stage of lactation: early, middle, and late, with 26 animals per group. Data were analyzed using univariate descriptive statistics and non-parametric tests. The results showed that average serum ceramide concentrations in early lactation were 33.28 ng/ml, in mid-lactation 32.55 ng/ml, and in late lactation 28.55 ng/ml. When comparing the lactation periods, no statistically significant differences were found (p=0.422). Similarly, no significant differences were found when comparing concentrations between primiparous and multiparous mothers (p=0.831). Likewise, no significant correlations were found between serum ceramide concentrations and the variables of days open, days of milk production, or milk yield. It is concluded that under the conditions of this study, serum ceramide concentrations did not show significant differences. However, the observed trends suggest that ceramide concentrations may be related to metabolic adaptations, especially during periods of increased energy mobilization.