Correlación de la paratohormona con la hipocalcemia sintomática en el posoperatorio precoz de tiroidectomía total en el Hospital José Carrasco Arteaga periodo 2017 - 2018

Abstract

Background: Hypocalcemia is a frequent complication after thyroid surgery and may be symptomatic or asymptomatic. Many factors have been related to symptomatic hypocalcemia, such as: parathyroid hormone, age, surgery time and type of surgery.

Objective: To determine the correlation of parathyroid hormone with symptomatic hypocalcemia in the early postoperative period of patients with a total thyroidectomy between 2017 and 2018 at José Carrasco Arteaga Hospital.

Method and materials: Analytical study of paratohormone levels after 1 hour and 6 hours post-surgery, age, surgery time, type of surgery, and pre-operatory cytology with clinical manifestations of hypocalcemia. The sample consisted of 171 patients who underwent a total thyroidectomy with or without level VI lymph node emptying of any etiology at José Carrasco Arteaga Hospital in the period 2017-2018.

Results: The prevalence of symptomatic hypocalcemia was 43.8%. A significant association of the clinical manifestations of hypocalcemia was found with low levels of parathyroid hormone at 1 and 6 hours post-surgery, a surgery time longer than 120 minutes and total thyroidectomy with a level VI lymph node emptying (p <0.05). On the other hand, the group older than 50 years (p 0.711) and the malignant pathology (p 0.751) are not significantly related to the presence of hipocalcemia symptomatology.

Conclusions: Paratohormone levels, operative time and type of surgery are related to symptomatic hypocalcemia. The measurement of paratohormona after 1 hour post-surgery has the same prognostic value as the one obtained 6 hours later to predict the development of the symptomatology