Determinación de paratohormona y su relación con creatinina sérica y microalbuminuria como indicador de disminución de la función renal en pacientes diabéticos del centro médico Donum

Abstract

The objective was determinate the Parathyroid hormone (PTH) as an indicator of renal function decrease, in relation to other indicators, such as Creatinine and Microalbuminuria. A descriptive, co-relational, non experimental, and cross-sectional study during the period May-June 2013. It took a total of seventy direct and intentional samples, who have been diagnosed over a period of ten years as study group. The samples were processed in the Laboratory ofPublicServiceandClinical Analysis Laboratoryof the University ofCuenca. The results were filed on in a database in the program MICROSOFT EXCEL v. 2007 and processed with SPSS STATISTICS V. 17.0. From the taken sample, the average age was 59, 38 years with a predominance of the female gender (64 %), the 68% presented normality in the determinations, 32% had altered values which 2 patients with 9 and 10 years of diagnosis presented all parameters high. Thepositive and negative controlgroupsconfirmedelevated and normalvaluesrespectively. The sample was divided into two groups: group 1 (1 to 5 years of diagnosis) and group 2 (6 to 10 years of diagnosis), the analysis was performed separately in each group, both were statistically comparable (p>0.05). The averages of thevariablesin group 2 werehigher than thosein group 1. The association PTH-Creatinine was presented in group 1 (p<0.05) but not in group 2 (p>0.05), the associationsPTH- Microalbuminuria and PTH-Years anddiagnosis were discardedfor the two groups(p>0.05).