Características clínicas, laboratoriales y terapéuticas en pacientes con lupus eritematoso sistémico del Hospital Vicente Corral Moscoso en el año 2019

Abstract

BACKGROUND: Systemic Lupus Erythematosus (SLE) is a worldwide disease consisting of an autoimmune inflammatory state that contributes to a clinical spectrum of multisystemic presentation. OBJECTIVE: to determine the frequency of clinical, laboratory and therapeutic characteristics in patients with SLE of the Vicente Corral Moscoso Hospital in 2019. MATERIALS AND METHODS: it is a descriptive study. Data collection was carried out from the medical records of patients diagnosed with SLE at the Vicente Corral Moscoso Hospital during the year 2019. Sociodemographic, clinical, laboratory, treatment and disease activity data from electronic medical records from the patients were analyzed. All data was analyzed with the Epi Info 7 program and the database was managed on the Microsoft Excel platform. RESULTS: a population of 91 patients diagnosed with SLE was studied, the average age was 34.5 years; more than half of the population studied (51.65%) is single; the most prevalent occupation was housework (37,36). The most frequent clinical characteristics were arthralgia (47.25%), malar rash (38.46%) and asthenia (36.26%). The most frequently found immunological markers were antinuclear antibodies (80.49%) and anti dsDNA (52.63%). The most frequently used treatment was corticosteroids in 81.32% of patients. CONCLUSION: SLE is a multisystem disease that mainly affects women of childbearing age, the most prevalent manifestation was arthralgia, the predominant immunological marker was antinuclear antibodies and the most used treatment was corticosteroids.