Actividad ansiolítica y antidepresiva de Coriandrum sativum: una revisión bibliográfica

Abstract

Coriander (Coriandrum sativum), a member of the Apiaceae family, is among the most used medicinal plants and has important nutritional and medicinal properties, among which are anxiolytic and antidepressant properties. The purpose of this titration work is to systematize the information on the anxiolytic and antidepressant activities of Coriandrum sativum depending on the type of extract and the methodology used in the experimental trials reported in the scientific articles found through a bibliographic review in different digital databases. Where the effect produced was analyzed in comparison with the anxiolytic and/or antidepressant drug. The results showed that cilantro (Coriandrum sativum), with its main component which is linalool, in its essential oil form, has been shown to have similar effects to drugs such as benzodiazepines (Diazepam, Clonazepam) in the management of animal models (mice, zebras, fish) with induced anxiety, as well as with antidepressant medications such as fluoxetine, in rodents with depression. Concluding that Coriandrum sativum has demonstrated both anxiolytic and antidepressant properties in animal models, it is therefore suggested to undertake other experimental studies in preclinical phases with other models and clinical phases in humans.