Dímero D en pacientes con SARS-Cov2 del Hospital Universitario del Río, Cuenca 2020-2021

Abstract

The coronavirus is a spherical virus similar to a crown formed by glycoproteins on the envelope. It is characterized by excessive production of inflammatory factors, which leads to an inflammatory storm, causing multi-organ conditions and liver, neurological, and cardiac problems and alterations in coagulation. The latter condition is called immunothrombosis, meaning the performance of the immune system - coagulation, as a response to infection by microorganisms and to prevent its spread. When these mechanisms are indiscriminately activated as a result of a systemic infection, coagulopathies occur. Methodology: This is a retrospective, cross-sectional, and descriptive study. D-Dimer tests in patients with SARS-CoV-2, who received medical care at Hospital Universitario del Río, in Cuenca, from 2020 to 2021, were analyzed. The universe and the sample both comprised patients with SARS-CoV-2 who had undergone D-Dimer tests. Data was analyzed using Microsoft Excel and IBM SPSS v25 software and simple and contingency tables. Results showed that out of 476 patients with SARS-CoV-2, 30.5% reported increased D-Dimer levels, over 501 ng/ml, mostly affecting people over 71 years of age (46.90%); males (61.38%); hospitalization area (50.34%).