Correlación entre la calprotectina fecal y hallazgos patológicos endoscópicos en pacientes con dispepsia atendidos en el Centro de Especialidades en gastroenterología González en el período enero-diciembre 2019

Abstract

Background: When approaching a patient consulting for gastrointestinal symptoms, differentiating an organic gastrointestinal disorder from a wide range of functional disorders can be a complicated task due to their similar symptoms. Given this, Fecal Calprotectin (FC) appears, a non-invasive, inexpensive and easy-to-apply test. Objective: To determine the correlation between FC and endoscopic pathological findings in patients with dyspepsia treated at the ¨González¨ Gastroenterology Specialty Center in the period January-December 2019. Methodology: Descriptive correlation study in patients with dyspepsia. Patients treated at the "González" Gastroenterological Center during the period January - December 2019 were included. The information was collected using forms prepared by the authors. Chi-square (X²) was used to evaluate statistical significance. Correlations between variables were determined using Spearman's Rho correlation coefficient. A p value less than 0.05 was considered statistically significant. Results: The sample consisted of 149 patients, of which 56.8% (n = 84) were female and 30.9% (n = 46) were ≥ 65 years old. The average general age was 56 ± 17 years. Statistical significance was found between CF positivity (≥50 μg / g) and variables such as age group (p = 0.031), pathological findings (p=0.001) and diagnosed pathologies (p = 0.015). CF positivity was positively and moderately correlated with alarm signs (r = 0.437) and weakly with pathological findings (r = 0.298). Conclusions: Fecal calprotectin was positively correlated with pathological findings in endoscopic examinations in patients with dyspepsia.