Deregulation of energy metabolism as a cause and consequence of oncogenic process: review of literature
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Date
2016
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Abstract
The reprogramming of energy metabolism is an emerging hallmark of cancer that has not yet been demonstrated in all tumor models, and there are aspects which still not entirely clear. This review enrolled and analyzed data from the last 20 years regarding the proposed theme; and it allowed to conclude that the deregulation of energy metabolism is a key factor in the initiation and progression of tumors, behaving as a cause and consequence.
Resumen
The reprogramming of energy metabolism is an emerging hallmark of cancer that has not yet been demonstrated in all tumor models, and there are aspects which still not entirely clear. This review enrolled and analyzed data from the last 20 years regarding the proposed theme; and it allowed to conclude that the deregulation of energy metabolism is a key factor in the initiation and progression of tumors, behaving as a cause and consequence.
Keywords
Glycolysis, Warburg phenomenon, Energy metabolism, Cancer