Correlación entre microalbuminuria y el conciente albúmina/creatinina en pacientes diagnosticados de diabetes mellitus

Abstract

The aimed was determine the correlation between techniques of Microalbumin in urine for 24 hours and the albumin/creatinine ratio in a first morning urine specimen, and validate this one as an indicator of kidney damage. Case-control study, cross-sectional correlational, was done May through August 2013. The study group of 90 patients was chosen for convenience; 60 patients with a Diabetes Mellitus Type I or II diagnostic, and without kidney damage, 15 patients with renal failure as positive control and, 15 patients as negative control who didn’t have Diabetes Mellitus or Kidney Disease diagnostic. Samples were processed in “Casa de la Diabetes” Foundation, “Universidad de Cuenca” Clinical Analysis Laboratory and “ClínicaHumanitaria Pablo Jaramillo Crespo” Foundation. The results obtained during the analysis was stored in a database on Microsoft Office Excel v. 2007 and precessed in SPSS STATISTICS v. 19.0. In the study sample prevalence of Diabetes Mellitus Type II was observed (93.33 %), the average age was 57.75. The percentages of normal and altered values in the different parameters of the overall study population distributed as follows; Microalbuminuria in urine 24 hours, 66.67% normal and 33.33% altered Microalbuminuria in morning urine, 73.33% normal and 26.67% altered; ratio albumin / creatinine, 71.67% normal and 28.33% altered. Also we observed that the altered values were independent of age Diabetes diagnostic. The correlation between Microalbumin in urine for 24 hours and the albumin/creatinine ratio in a first morning urine specimen, determined by the Pearson Correlation Ratio and Chi square test was r=0.924 and p < 0.05 respectively, it proved that the correlation betweet this parameters is strong and significant statistically, validating the ratio albumin/creatinina as preventive and diagnostic test for kidney damage.