Investigación del cromosoma filadelfia en leucemia mieloide crónica y leucemia linfoblástica

Abstract

In the period between January 1 and December 31, 2000, at the Cancer Institute Hospital of Cuenca, in 32 patients with chronic myeloid leukemia and acute Linfoblática the presence of the Philadelphia chromosome as a tumor marker chromosome was investigated. ranging in age from 1 to 62 years was found with an average of 22.5 plus or minus 18.21. 59.4 percent of the sample were male and 40.6 percent female. 71.9 of patients had acute lymphoblastic leukemia and 28.1 percent had chronic myeloid leukemia. The Philadelphia chromosome was found in 37.5 percent of the sample and 62.5 percent was not present. In 21 percent of the total group there was metaphase. The age group that had more impact on the Philadelphia chromosome was that of 1-9 years accounted for 12.5 percent of the sample. In 88.88 percent of patients with chronic myeloid leukemia Philadelphia chromosome we found. The literature reports 95 percent. In patients with Acute Leukemia Linfoblática Philadelphia chromosome found only in 17.93 percent. The literature provides 80 to 90 percent