Estado de control del índice internacional normalizado en fibrilación auricular no valvular con antagonistas de la vitamina k. Hospital José Carrasco Arteaga. Cuenca. 2018

Abstract

Background: Atrial fibrillation (AF) is one of the most common arrhythmic disorders. The cardio embolic events are the most frequent complication, they are preventable by anticoagulation. Among the most widely used drugs are vitamin K antagonists that require periodic monitoring of prothrombin time using the International Normalized Ratio (INR), considered normal between 2 and 3.Objective: to evaluate the status of INR control in patients with non-valvular atrial fibrillation treated with vitamin K antagonists in the outpatient service of the José Carrasco Arteaga Hospital.Methodology: a descriptive, cross-sectional study of retrospective data was carried out; the data were taken out from the medical records of 108 patients with a diagnosis of non-valvular atrial fibrillation who attended an outpatient cardiology consultation during 2018 at the José Carrasco Arteaga Hospital. It was considered as inadequate control when the time in therapeutic range (TRT) is less than 60% by the direct method and less than 65% by the Rosendaal method.Results: the study showed that the INR control status was adequate in 47.2% of patients by the direct method, while by the Rosendaal method, it was 41.7%. The 100% used warfarin. In the group of patients with poor control, there was evidence of an older age and a higher score on the HAS-BLED scale (p <0.0001).Conclusions: The INR control status was poor in more than 50% of patients by both methods, so these patients did not benefit from anticoagulant therapy with vitamin K antagonists.