Associated factors to microalbuminuria and chronic kidney disease in patients from the Hospital Básico de Paute, Ecuador

Abstract

Objective: To determine the associated factor to microalbuminuria and Chronic Kidney Disease (CKD) in diabetic patients of the Hospital Basico de Paute, Ecuador. Materials and methods: This was a descriptive and cross-sectional study in patients with type 2 diabetes mellitus of the Hospital Básico de Paute diabetes club during the period January to August 2018, a questionnaire validated by 2 experts in diabetes mellitus was used, the following data was reported: personal, anthropometric, microalbuminuria levels and glomerular filtration rate. Results: Out of the 80 patients evaluated, 73.8% (n=59) were female, microalbuminuria was present in 20% (n=16) of the cases and the majority of subjects were in stage 2 of CKD when applying the MDRD-4 formula. The main factor associated with microalbuminuria was occupation, with a lower frequency in patients with household activities (<30 mg/24 hours: 71.9% vs 30-300 mg/24 hours: 50%; P<0.01). The patients with the highest percentage of microalbuminuria were farmers / ranchers and public / private employees. Regarding the factors associated with the stage of CKD, the frequency of subjects >70 years of age increased as the Glomerular Filtration Rate decreased (Stage 1: 6.7% vs. Stage 3: 53.8%). Conclusion: The patients of the Hospital Basico de Paute diabetes club, Ecuador have a prevalence of microalbuminuria similar to previous reports, especially Latin America, with a classification of CKD in the first stages. Being the laboral status the main factor associated to microalbuminuria and the age related to the stage of CKD.