Características de la esclerosis sistémica, en pacientes de los hospitales Vicente Corral Moscoso y José Carrasco Arteaga durante el período enero 2008 – junio 2015

Abstract

Background: Systemic sclerosis is a chronic, rare connective tissue disease of unknown etiology that primarily affects females. The disease is characterized by having vascular disease, autoimmunity and fibrosis. Produced multiple organ damage, generates significant social and health impacts and to date there is no cure.

Objective: To determine the characteristics of the Systemic Sclerosis patients at the Hospital Vicente Corral Moscoso and José Carrasco Arteaga.

Methods and Materials: It is a quantitative, descriptive and retrospective study. The universe is comprised of patients diagnosed with systemic sclerosis in both hospitals. The information was collected from medical records and analyzed in Microsoft Excel 2013 and SPSS 19. Quantitative and qualitative variables were used, showing through frequencies and percentages. A level of statistical association for p < 0.05 was considered.

Results: Systemic sclerosis is more common in women. The limited form is predominant. The most common clinical manifestations are skin, followed by musculoskeletal and Raynaud's Syndrome. The group of 50-64 years is showing greater degree of general involvement; in younger people skin and musculoskeletal affectations are more frequent. Antinuclear antibodies were the best diagnostic value, being positive in more than 70 % of patients. The most common treatments are based on controlling symptoms, paracetamol being the most used (80.4 %).

Conclusions: Systemic sclerosis affects more women than men; the most common age group is between 25-64 years. The limited form prevails over the diffuse. Its main clinical manifestations are skin.