Publication: Integrin α6 (CD49f), the microenvironment and cancer stem cells
| dc.contributor.author | Czarnowski, Daniel | |
| dc.contributor.author | Gerard J., Madlambayan | |
| dc.contributor.author | Tyler, Parsons | |
| dc.contributor.author | Bigoni Ordóñez, Gabriele Davide | |
| dc.contributor.author | Luis G., Villa Diaz | |
| dc.date.accessioned | 2021-05-25T22:27:09Z | |
| dc.date.available | 2021-05-25T22:27:09Z | |
| dc.date.issued | 2019 | |
| dc.description.abstract | Cancer is a highly prevalent and potentially terminal disease that affects millions of indi- viduals worldwide. Here, we review the literature exploring the intricacies of stem cells bearing tumori- genic characteristics and collect evidence demonstrating the importance of integrin 6 (ITGA6, also known as CD49f) in cancer stem cell (CSC) activity. ITGA6 is commonly used to identify CSC popula- tions in various tissues and plays an important role sustaining the self-renewal of CSCs by interconnect- ing them with the tumorigenic microenvironment. | |
| dc.identifier.doi | 10.2174/1574888X13666181002151330 | |
| dc.identifier.issn | 1574-888X, e2212-3946 | |
| dc.identifier.uri | http://dspace.ucuenca.edu.ec/handle/123456789/36239 | |
| dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/30280675/ | |
| dc.language.iso | es_ES | |
| dc.source | Current Stem Cell Research & Therapy | |
| dc.subject | Laminins | |
| dc.subject | Integrin 6 | |
| dc.subject | Tumor microenvironment | |
| dc.subject | Cancer stem cells | |
| dc.subject | Cell signalling | |
| dc.subject | Self-renewal | |
| dc.title | Integrin α6 (CD49f), the microenvironment and cancer stem cells | |
| dc.type | ARTÍCULO | |
| dc.ucuenca.afiliacion | Czarnowski, D., Oakland University, Rochester, Estados unidos | |
| dc.ucuenca.afiliacion | Bigoni, G., Universidad Nacional Autónoma de México, México City, México | |
| dc.ucuenca.afiliacion | Tyler, P., Oakland University, Rochester, Estados unidos | |
| dc.ucuenca.afiliacion | Gerard, M., Oakland University, Rochester, Estados unidos | |
| dc.ucuenca.afiliacion | Luis, V., Oakland University, Rochester, Estados unidos | |
| dc.ucuenca.areaconocimientofrascatiamplio | 1. Ciencias Naturales y Exactas | |
| dc.ucuenca.areaconocimientofrascatidetallado | 1.6.1 Biología Celular | |
| dc.ucuenca.areaconocimientofrascatiespecifico | 1.6 Ciencias Biológicas | |
| dc.ucuenca.areaconocimientounescoamplio | 05 - Ciencias Físicas, Ciencias Naturales, Matemáticas y Estadísticas | |
| dc.ucuenca.areaconocimientounescodetallado | 0511 - Biología | |
| dc.ucuenca.areaconocimientounescoespecifico | 051 - Ciencias Biológicas y Afines | |
| dc.ucuenca.correspondencia | Luis G., Villa Diaz, luisvilladiaz@oakland.edu | |
| dc.ucuenca.embargoend | 2050-12-30 | |
| dc.ucuenca.embargointerno | 2050-12-30 | |
| dc.ucuenca.idautor | Sgrp-4239-3 | |
| dc.ucuenca.idautor | 1711901429 | |
| dc.ucuenca.idautor | 0000-0002-4026-636X | |
| dc.ucuenca.idautor | Sgrp-4239-4 | |
| dc.ucuenca.idautor | 0000-0001-5709-9054 | |
| dc.ucuenca.urifuente | https://www.eurekaselect.com/node/637/current-stem-cell-research-therapy/issue/14/2598/5/9114 | |
| dc.ucuenca.version | Versión publicada | |
| dc.ucuenca.volumen | Volumen 14, número 5 | |
| dspace.entity.type | Publication | |
| relation.isAuthorOfPublication | 64362eb2-b1a4-44ca-92cc-01adbaf081f7 | |
| relation.isAuthorOfPublication.latestForDiscovery | 64362eb2-b1a4-44ca-92cc-01adbaf081f7 |
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