Person:
Ochoa Avilés, Angélica María

Birth Date

1983-01-23

ORCID

0000-0001-7926-3644

Scopus Author ID

55385603500

Afiliación

Universidad de Cuenca, Cuenca, Ecuador
Universidad de Cuenca, Departamento de Biociencias, Cuenca, Ecuador
Universidad de Cuenca, Facultad de Ciencias Químicas, Cuenca, Ecuador

País

Ecuador

Organizational Units

Organizational Unit

Facultad de Ciencias Químicas

Fundada en 1955 como la Escuela de Química Industrial, la facultad ha sido un pilar fundamental en la formación de profesionales altamente capacitados, comprometidos con el desarrollo de la ciencia, la educación y el bienestar social. La Facultad de Ciencias Químicas pone a consideración su trabajo académico, investigativo y de vinculación con la sociedad, desarrollado a través de la práctica de una docencia de calidad, investigación e innovación en su área de estudio. Desde su oficio de conocimiento se permite contribuir a la sociedad con cuatro carreras: Bioquímica y Farmacia, Ingeniería Química, Ingeniería Ambiental e Ingeniería Industrial. Su carta de presentación en la Academia, la coloca como una dependencia dinámica, donde confluye la solidez de una trayectoria de más de sesenta años. Aquí se trabaja en una continua formación de pregrado y posgrado de la más alta calidad, mediante la mejora continua con la innovación y a la vanguardia de las ciencias químicas.

Job Title

Profesor (T)

Last Name

Ochoa Avilés

First Name

Angélica María

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Now showing 1 - 10 of 21

Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants
(2015) Danaei, Goodarz; Ochoa Avilés, Angélica María; Ezzati, Majid; Andrade Tenesaca, Dolores Susana; Zheng, Yao
Background Diabetes has been defi ned on the basis of diff erent biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA1c. We assessed the eff ect of diff erent diagnostic defi nitions on both the population prevalence of diabetes and the classifi cation of previously undiagnosed individuals as having diabetes versus not having diabetes in a pooled analysis of data from population-based health examination surveys in diff erent regions. Methods We used data from 96 population-based health examination surveys that had measured at least two of the biomarkers used for defi ning diabetes. Diabetes was defi ned using HbA1c (HbA1c ≥6·5% or history of diabetes diagnosis or using insulin or oral hypoglycaemic drugs) compared with either FPG only or FPG-or-2hOGTT defi nitions (FPG ≥7·0 mmol/L or 2hOGTT ≥11·1 mmol/L or history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated diabetes prevalence, taking into account complex survey design and survey sample weights. We compared the prevalences of diabetes using diff erent defi nitions graphically and by regression analyses. We calculated sensitivity and specifi city of diabetes diagnosis based on HbA1c compared with diagnosis based on glucose among previously undiagnosed individuals (ie, excluding those with history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated sensitivity and specifi city in each survey, and then pooled results using a random-eff ects model. We assessed the sources of heterogeneity of sensitivity by meta-regressions for study characteristics selected a priori. Findings Population prevalence of diabetes based on FPG-or-2hOGTT was correlated with prevalence based on FPG alone (r=0·98), but was higher by 2–6 percentage points at diff erent prevalence levels. Prevalence based on HbA1c was lower than prevalence based on FPG in 42·8% of age–sex–survey groups and higher in another 41·6%; in the other 15·6%, the two defi nitions provided similar prevalence estimates. The variation across studies in the relation between glucose-based and HbA1c-based prevalences was partly related to participants’ age, followed by natural logarithm of per person gross domestic product, the year of survey, mean BMI, and whether the survey population was national, subnational, or from specifi c communities. Diabetes defi ned as HbA1c 6·5% or more had a pooled sensitivity of 52·8% (95% CI 51·3–54·3%) and a pooled specifi city of 99·74% (99·71–99·78%) compared with FPG 7·0 mmol/L or more for diagnosing previously undiagnosed participants; sensitivity compared with diabetes defi ned based on FPGor-2hOGTT was 30·5% (28·7–32·3%). None of the preselected study-level characteristics explained the heterogeneity in the sensitivity of HbA1c versus FPG. Interpretation Diff erent biomarkers and defi nitions for diabetes can provide diff erent estimates of population prevalence of diabetes, and diff erentially identify people without previous diagnosis as having diabetes. Using an HbA1c-based defi nition alone in health surveys will not identify a substantial proportion of previously undiagnosed people who would be considered as having diabetes using a glucose-based test.
Revisión sistemática de estudios sobre inocuidad alimentaria en Cuenca, Ecuador, periodo 1981-2017
(2020) Ortiz Ulloa, Silvia Johana; Castro Arteaga, Evelyn Michelle; Ochoa Avilés, Angélica María; Donoso Moscoso, Silvana Patricia
Objetivo: Evaluar la evidencia existente sobre inocuidad alimentaria en el cantón Cuenca, Ecuador. Materiales y métodos: Se realizó una revisión sistemática de los estudios en inocuidad alimentaria (microorganismos, contaminantes y adulterantes) durante el período 1981-2017. Resultados: Inicialmente se identificaron 640 estudios. Luego del análisis de los criterios de inclusión y exclusión, se incluyeron 40 estudios relacionados a evaluaciones microbiológicas (67.5%), pesticidas, parásitos y antibióticos (7.5%), conservantes y metales (10%) y toxinas (15%). Discusión: En los estudios se recalca la necesidad de implementar medidas de higiene y monitoreo, control en la manipulación, transporte y almacenamiento, control de los alimentos frescos cuya calidad no está regida por normativas nacionales, capacitar a los manipuladores y vendedores ambulantes. Esta revisión proporciona una base racional para toma de decisiones y desarrollo de medidas preventivas y correctivas; así como también propone los criterios mínimos de muestreo y análisis para discriminar y comparar estudios en esta problemática.
Trends in cardiometabolic risk factors in the Americas between 1980 and 2014: a pooled analysis of population-based surveys
(2020) Miranda, Jaime J; Carrillo Larco, Rodrigo M; Ferreccio, Catterina; Hambleton, Ian R; Bentham, James; Lotufo, Paulo A; Bixby, Honor; Taddei, Cristina; Andrade Tenesaca, Dolores Susana; Bernabe Ortiz, Antonio; Bettiol, Heloisa; Boggia de Izaguirre, josé Gabriel; Donoso Moscoso, Silvana Patricia; Ochoa Avilés, Angélica María; Di Cesare, Mariachiara; Nieto Martínez, Ramfis; Bin, Zhou; Hajifathalian, Kaveh; Abarca Gómez, Leandra; Acosta Cazares, Benjamin; Aguilar Salinas, Carlos A.; Assuncao , Maria Cecília F.; Barceló, Alberto; Dornellas de Barros, Aluísio Jardim; Gomes de Barros, Mauro Virgilio; Bata, Iqbal; Batista, Rosangela L; Brewster, Lizzy M; Cardoso, Viviane C; Chan, Queenie; Destro Christofaro, Diego Giulliano
Background Describing the prevalence and trends of cardiometabolic risk factors that are associated with noncommunicable diseases (NCDs) is crucial for monitoring progress, planning prevention, and providing evidence to support policy efforts. We aimed to analyse the transition in body-mass index (BMI), obesity, blood pressure, raised blood pressure, and diabetes in the Americas, between 1980 and 2014. Methods We did a pooled analysis of population-based studies with data on anthropometric measurements, biomarkers for diabetes, and blood pressure from adults aged 18 years or older. A Bayesian model was used to estimate trends in BMI, raised blood pressure (systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg), and diabetes (fasting plasma glucose ≥7·0 mmol/L, history of diabetes, or diabetes treatment) from 1980 to 2014, in 37 countries and six subregions of the Americas. Findings 389 population-based surveys from the Americas were available. Comparing prevalence estimates from 2014 with those of 1980, in the non-English speaking Caribbean subregion, the prevalence of obesity increased from 3·9% (95% CI 2·2–6·3) in 1980, to 18·6% (14·3–23·3) in 2014, in men; and from 12·2% (8·2–17·0) in 1980, to 30·5% (25·7–35·5) in 2014, in women. The English-speaking Caribbean subregion had the largest increase in the prevalence of diabetes, from 5·2% (2·1–10·4) in men and 6·4% (2·6–10·4) in women in 1980, to 11·1% (6·4–17·3) in men and 13·6% (8·2–21·0) in women in 2014). Conversely, the prevalence of raised blood pressure has decreased in all subregions; the largest decrease was found in North America from 27·6% (22·3–33·2) in men and 19·9% (15·8–24·4) in women in 1980, to 15·5% (11·1–20·9) in men and 10·7% (7·7–14·5) in women in 2014. Interpretation Despite the generally high prevalence of cardiometabolic risk factors across the Americas, estimates also showed a high level of heterogeneity in the transition between countries. The increasing prevalence of obesity and diabetes observed over time requires appropriate measures to deal with these public health challenges. Our results support a diversification of health interventions across subregions and countrie
Indoor Environmental Quality In Preschool Buildings In an Andean City In Ecuador
(2024) Ochoa Avilés, Angélica María; Escandón Dután, Samuel Adrián; Ochoa Avilés, María Cristina
Indoor environmental quality has been associated with the health and wellbeing of building occupants; nevertheless, there is limited evidence in this regard for Latin American schools. This research aimed to characterize indoor environmental quality in public and private preschools in an Andean city in Ecuador. Data collection com-prised onsite monitoring for the thermal-humidity microclimate of 90 classrooms in 30 preschools in Cuenca-Ecuador (March-August 2018). Infrared thermography and direct observation were applied to determine dampness. Classrooms seemed to be inadequate thermal-humidity microclimates; only a few maintained a comfortable temperature (6%) and relative humidity (11%) throughout the shift. When compar-ing public and private schools, in private schools, temperatures below the comfort range (61.3% in private schools vs 31.4% in public schools, p<0.001) and relative humidity measures above the comfort range were more frequent (74.3% in private schools vs. 58.6% in public schools, p<0.001). Hollow blocks were the primary construction material in private and public schools. Sixty-four per cent of private schools operated in adaptive, reused buildings, vs 19% in public schools (p<0.05). Infrared thermography confirmed dampness in 26% (n=23) of the classrooms in the covering structures indoors (15% in public vs 33% in private schools, p<0.05). This research reveals the urgent need to develop specific regulations and control mechanisms for building sustainable and healthy environments for preschools in Ecuador.
Results from Ecuador’s 2018 report card on physical activity for children and youth
(2018) Andrade Tenesaca, Dolores Susana; Romero Sandoval, Natalia Cristina; Orellana Vintimilla, Daniel Augusto; Contreras Calle, Wilson Teodoro; Pillco Chuqui, Jose Luis; Andrade Muñoz, Diana Jesús; Martín, Miguel; Donoso Moscoso, Silvana Patricia; Ochoa Avilés, Angélica María
International initiatives like the Active Healthy Kids Global Alliance (AHKGA) have emerged to support monitoring and surveillanceofphysicalactivity,physical ﬁtness,sedentarybehavioranditssocialandenvironmentalinﬂuencesamongchildrenand adolescents.1,2 The standardized methodology proposed by AHKGA focuses on the development of a Report Card, allows the compilation of knowledge gaps and highlights the most urgent needsandproblemsthat shouldbeconsidered by policymakersto promote an active healthy lifestyle among children and youth withineachcountry.2 Thispapersummarizesthe ﬁrstresultsofthe Ecuadorian 2018 Report Card (Figure 1) based on the AHKGA methodology.
Prevalence and risk factors for asthma, rhinitis, eczema, and atopy among preschool children in an andean city
(2020) Ochoa Avilés, María Cristina; Morillo Argudo, Diana Alexandra; Rodriguez, Alejandro; Cooper , Philip John; Andrade Tenesaca, Dolores Susana; Molina Cando, Maria Jose; Parra Ullauri, Mayra Alejandra; Parra Ullauri, Andrea; Mejía Coronel, Julio Danilo; Neira Molina, Vivian Alejandra; Rodas Espinoza, Claudia Rosana; Ochoa Avilés, Angélica María
Background: Limited data are available on prevalence and associated risk factors for atopy and allergic diseases from high-altitude urban settings in Latin America. Objective: To estimate the prevalence of atopy, asthma, rhinitis, and eczema, and associations with relevant risk factors in preschool children in the Andean city of Cuenca. Methods: A cross-sectional study was undertaken using a representative sample of 535 children aged 3-5 years attending 30 nursery schools in the city of Cuenca, Ecuador. Data on allergic diseases and risk factors were collected by parental questionnaire. Atopy was measured by skin prick test (SPT) reactivity to a panel of relevant aeroallergens. Associations between risk factors and the prevalence of atopy and allergic diseases were estimated using multivariable logistic regression. Results: Asthma symptoms were reported for 18% of children, rhinitis for 48%, and eczema for 28%, while SPT reactivity was present in 33%. Population fractions of asthma, rhinitis, and eczema attributable to SPT were 3.4%, 7.9%, and 2.9%, respectively. In multivariable models, an increased risk of asthma was observed among children with a maternal history of rhinitis (OR 1.85); rhinitis was significantly increased in children of high compared to low socioeconomic level (OR 2.09), among children with a maternal history of rhinitis (OR 2.29) or paternal history of eczema (OR 2.07), but reduced among children attending daycare (OR 0.64); eczema was associated with a paternal history of eczema (OR 3.73), and SPT was associated with having a dog inside the house (OR 1.67). Conclusions: A high prevalence of asthma, rhinitis, and eczema symptoms were observed among preschool children in a high-altitude Andean setting. Despite a high prevalence of atopy, only a small fraction of symptoms was associated with atopy. Parental history of allergic diseases was the most consistent risk factor for symptoms in preschool children.
Sugar-sweetened beverage intakes among adults between 1990 and 2018 in 185 countries
(2023) Ortiz Ulloa, Silvia Johana; Ochoa Avilés, Angélica María
Sugar-sweetened beverages (SSBs) are associated with cardiometabolic diseases and social inequities. For most nations, recent estimates and trends of intake are not available; nor variation by education or urbanicity. We investigated SSB intakes among adults between 1990 and 2018 in 185 countries, stratified subnationally by age, sex, education, and rural/urban residence, using data from the Global Dietary Database. In 2018, mean global SSB intake was 2.7 (8 oz = 248 grams) servings/week (95% UI 2.5-2.9) (range: 0.7 (0.5-1.1) in South Asia to 7.8 (7.1-8.6) in Latin America/Caribbean). Intakes were higher in male vs. female, younger vs. older, more vs. less educated, and urban vs. rural adults. Variations by education and urbanicity were largest in Sub-Saharan Africa. Between 1990 and 2018, SSB intakes increased by +0.37 (+0.29, +0.47), with the largest increase in Sub-Saharan Africa. These findings inform intervention, surveillance, and policy actions worldwide, highlighting the growing problem of SSBs for public health in Sub-Saharan Africa
Resultados de la investigación del programa “Alimentación Nutrición y Salud” efectuado en Nabón en los años 2008-2009
(2014) Ochoa Avilés, Angélica María; Andrade Tenesaca, Dolores Susana; Donoso Moscoso, Silvana Patricia
A school-based intervention improves physical fitness in Ecuadorian adolescents: a cluster-randomized controlled trial
(2014) Andrade Tenesaca, Dolores Susana; Ochoa Avilés, Angélica María; Andrade Muñoz, Diana Jesús; Rojas Reyes, Rosendo Iván; Donoso Moscoso, Silvana Patricia; Kolsteren, Patrick
Background: Effective lifestyle interventions are needed to prevent noncommunicable diseases in low- and middle-income countries. We analyzed the effects of a school-based health promotion intervention on physical fitness after 28 months and explored if the effect varied with important school characteristics. We also assessed effects on screen time, physical activity and BMI. Methods and results: We performed a cluster-randomized pair matched trial in schools in urban Ecuador. The intervention included an individual and environmental component tailored to the local context and resources. Primary outcomes were physical fitness (EUROFIT battery), screen time (questionnaires) and physical activity (accelerometers). Change in BMI was a secondary outcome. A total of 1440 grade 8 and 9 adolescents (intervention: n = 700, 48.6%) and 20 schools (intervention: n = 10, 50%) participated. Data of 1083 adolescents (intervention: n = 550, 50.8%) from 20 schools were analyzed. The intervention increased vertical jump (mean effect 2.5 cm; 95% CI 0.8-4.2; P = 0.01). Marginally insignificant, adolescents from the intervention group needed less time for speed shuttle run (intervention effect = −0.8 s, 95% CI −1.58-0.07; P = 0.05). The proportion of students achieving over 60 minutes of moderate-to-vigorous physical activity/day decreased over time with the change in proportion significantly less in the intervention schools (6 vs. 18 percentage points, P < 0.01). The intervention effect on speed shuttle run was significant in larger schools while the effect on vertical jump was larger in mixed gender school compared to small and female schools. The proportion of schools that met the recommendations for physical activity increased with 37% in intervention schools with half-day schedule compared to the controls in the pair. No significant effects were found on screen time and BMI. Measurement of physical activity in a subsample was a limitation. No adverse effects were reported. Conclusions: A school-based intervention with an individual and environment component can improve physical fitness and can minimize the decline in physical activity levels from childhood into adolescence in urban Ecuador.
Two years of school-based intervention program could improve the physical fitness among Ecuadorian adolescents at health risk: Subgroups analysis from a cluster-randomized trial
(2016) Andrade Tenesaca, Dolores Susana; Ochoa Avilés, Angélica María; Donoso Moscoso, Silvana Patricia; Ortiz Ulloa, Silvia Johana
Background Adolescents with overweight and poor physical fitness have an increased likelihood of developing cardiovascular diseases during adulthood. In Ecuador, a health promotion program improved the muscular strength and speed-agility, and reduced the decline of the moderate-to-vigorous physical activity of adolescents after 28 months. We performed a sub-group analysis to assess the differential effect of this intervention in overweight and low-fit adolescents. Methods We performed a cluster-randomized pair matched trial in schools located in Cuenca–Ecuador. In total 20 schools (clusters) were pair matched, and 1440 adolescents of grade 8 and 9 (mean age of 12.3 and 13.3 years respectively) participated in the trial. For the purposes of the subgroup analysis, the adolescents were classified into groups according to their weight status (body mass index) and aerobic capacity (scores in the 20 m shuttle run and FITNESSGRAM standards) at baseline. Primary outcomes included physical fitness (vertical jump, speed shuttle run) and physical activity (proportion of students achieving over 60 min of moderate–to-vigorous physical activity/day). For these primary outcomes, we stratified analysis by weight (underweight, normal BMI and overweight/obese) and fitness (fit and low fitness) groups. Mixed linear regression models were used to assess the intervention effect. Results The prevalence of overweight/obesity, underweight and poor physical fitness was 20.3 %, 5.8 % and 84.8 % respectively. A higher intervention effect was observed for speed shuttle run in overweight (β = −1.85 s, P = 0.04) adolescents compared to underweight (β = −1.66 s, P = 0.5) or normal weight (β = −0.35 s, P = 0.6) peers. The intervention effect on vertical jump was higher in adolescents with poor physical fitness (β = 3.71 cm, P = 0.005) compared to their fit peers (β = 1.28 cm, P = 0.4). The proportion of students achieving over 60 min of moderate-to-vigorous physical activity/day was not significantly different according to weight or fitness status. Conclusion Comprehensive school-based interventions that aim to improve diet and physical activity could improve speed and strength aspects of physical fitness in low-fit and overweight/obese adolescents.