Browsing by Author "Guevara Serrano, Karen Dayana"

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    Osteoporosis en pacientes con artritis reumatoide que reciben corticoides a dosis bajas
    (2020) Guevara Serrano, Karen Dayana; Guzhñay Bernal, Silvia Maribel
    Osteoporosis (OP) is a frequent comorbidity in patients with rheumatoid arthritis (RA) who take low doses of glucocorticoids (GCs) (<7.5mg), which causes malabsorption of calcium, decreased bone mass and risk of fracture. Objective: to establish the frequency of OP and low bone mineral density (BMD) in patients with RA who take low doses of GCs from the Vicente Corral Moscoso Hospital (HVCM). Methodology: a descriptive, cross-sectional study was carried out in patients with RA who were attended in the HVCM outpatient clinic, who receive disease-modifying anti-rheumatic drugs (DMARDs) and low doses of GCs in addition to conventional medication. The sample was calculated based on a frequency of 30% of OP. For the diagnosis of OP, axial densitometry (DXA) was used with WHO criteria. The information was processed in SPSS version 15.Results: the study was carried out with 161 patients with RA who took low doses of GCs, 96.3% were female, the age group from 40 to 64 years represented 60.2%, the majority made domestic chores 78.9%. The BMD in the lumbar spine was low with 39.1% and OP 37.9%; low BMD in the femoral neck 39.8% and OP 17.4%. Conclusions: frequency of OP and decreased BMD was found in RA patients taking low-dose GCs; being more frequent the OP and decreased BMD in people older than 64 years with RA and who take GCs for more than ten years
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    Osteoporosis y densidad mineral ósea baja en pacientes con artritis reumatoide, con ingesta de corticoides. Hospital Vicente Corral Moscoso. Cuenca.2018
    (Universidad de Cuenca, 2020-05-21) Guevara Serrano, Karen Dayana; Guzhñay Bernal, Silvia Maribel; Vintimilla Ugalde, Jaime Fernando
    Rheumatoid arthritis (RA) is a chronic inflammatory, sometimes refractory disease that may require low doses of glucocorticoids to relieve signs and symptoms, a drug that could produce a decrease in bone mass and osteoporosis with risk of fracture. OBJECTIVE: to determine the frequency of osteoporosis (OP) and low bone mineral density in patients with RA with intake of low doses of corticosteroids from Hospital Vicente Corral Moscoso. Cuenca 2018. METHODOLOGY: a retrospective descriptive, cross-sectional study in which the frequency of OP and low bone mineral density will be established in a sample of 161 patients diagnosed with RA treated with low doses of glucocorticoids (<7.5mg), who come to the external consultation of the rheumatology department in the outpatient area of the Hospital Vicente Corral Moscoso (HVCM), in the period from May 2017 to April 2018. The diagnosis of PO and decreased bone mineral density will be determined with the results of the double energy X-ray absorptiometry (DEXA, for its acronym in English). The statistical analysis will be through basal tables in addition to graphs and the Chi square test that allows to compare the observed distribution of the data. RESULTS: the study will establish the frequency of OP and low bone mineral density in patients with RA who take low doses of corticosteroids that go to the rheumatology department in the outpatient area of the Hospital Vicente Corral Moscoso in the period between May 2017 to April 2018.