Niveles de progesterona en las pacientes con amenaza de aborto en comparación con las pacientes con embarazo normal

Abstract

Introduction: Progesterone is a hormone essential for the maintenance of pregnancy. Progesterone has proved to be a useful biomarker for diagnosing early pregnancy failure. However their usefulness is still questionable due to the different cut-off points. Objective: Compare the values of progesterone in the patients with threatened miscarriage and normal pregnancy in the Hospital Vicente Corral Moscoso and José Carrasco Arteaga, Cuenca 2014. Material and methods: a descriptive cross-sectional study was conducted with a sample of 276 maternal with pregnancies less than 13 weeks of gestation. They were divided into two groups: a first group of 137 patients with threatened miscarriage and a second group with normal pregnancy. It was determined the value of progesterone in ng/ml in each patient. Comparing the average of the values of progesterone in each group by the student's t test, it was considered statistically significant difference values of p<0.05 . Results: The average age of the groups was 26.7 years, no differences were observed between the groups according to the average weight and height, p-values>0.05 . The average gestational age according to the date of the last menstrual period and the ultrasound is of 8.5 weeks for the group with threat of abortion and the group with normal pregnancy. The average levels of progesterone in the group of patients with threatened miscarriage is 15.18 ± 5.47 ng/ml and in the group with normal pregnancy is 18.30 ± 5.29 ng/ml, p-value=0.000