Eficacia y seguridad del sulfato de magnesio como coadyuvante en la analgesia postoperatoria de histerectomía abdominal, bajo anestesia general balanceada. Hospitales Vicente Corral Moscoso y José Carrasco Arteaga. Cuenca. 2013

Abstract

Background: this becomes a pressing problem in Ecuador, where there are still inconclusive aspects to be considered. Objective: to determine the effectiveness and safety of intravenous magnesium sulfate as an coadyuvant to postoperative analgesia for abdominal hysterectomy under general anesthetics. Vicente Corral Moscoso Hospital and Hospital José Carrasco Arteaga Cuenca, 2013. Material and Methods: a clinical, randomized, single-blind study was performed; it was formed by two equal groups of 78 patients that were scheduled for abdominal hysterectomy. Group "A" was administered 50mg / kg Magnesium sulphate, and 15 minutes of balanced general anesthesia. In addition, analgesics such as tramadol 2 mg / kg at the time of aponeurotic closure; after that 1 mg / kg was first given every 6 hours during postoperative care and after that ketorolac 30 mg trans-surgical.; while "Group B" was given balanced general anesthesia using the before mentioned parameters with the exception of administering magnesium sulfate. Pain intensity was measured by visual analog scales. Results: group A showed mild pain average 3.76 + 1.22 compared to the group B which recorded moderate pain average 5.05 + 1.42; this difference is statistically significant up to 4 hours postoperatively with p = 0.000. No group reported cases of anaphylactic reaction, hypotension; nausea, vomiting or respiratory depression: bradycardia occurs in the two groups, having no significant statistical difference. Conclusions: magnesium sulphate proved effective as adjunctive analgesia until 4 hours postoperatively, its administration is safe