Desensitizing and remineralizing agents used in the hypomineralization of molar incisors in pediatric population

Abstract

This review aims to summarize the available evidence on various desensitizing agents used in molar incisor hypomineralization (MIH) in the pediatric population. In MIH, calcification and maturation at the amelogenesis stage are compromised, affecting enamel mineralization. MIH affects quality of life through dental hypersensitivity, which is the response of the teeth to external stimuli, including temperature and pressure changes during chewing, affecting quality of life. A literature review was conducted in PubMed, Scopus, Science Direct, Scielo, and Google Scholar, focusing on searching for studies published between 2018 and 2023 whose data were independently collected and selected. A total of 2380 articles were collected, of which 10 studies met the eligibility criteria. These studies focused on agents used for remineralization and tooth sensitivity decrease. These agents include amorphous casein phosphopeptide, toothpastes composed of fluoride, arginine, hydroxyapatite, fluoride varnish, novamin, potassium nitrate, silver diamine fluoride and laser as a preventive method for tooth sensitivity. There has been evidence that various desensitizing agents have had a significant impact on remineralizing enamel, reducing dental sensitivity. More longitudinal studies are required to provide definitive and effective treatment plans for MIH patients.