Probióticos en la prevención de enterocolitis necrotizante en neonatos pretérminos del servicio de neonatología del Hospital Vicente Corral Moscoso. Cuenca 2012

Abstract

BACKGROUND: Studies show that probiotics decrease the frequency of necrotizing enterocolitis (NEC) in preterm infants, whose problem is very important in our region. OBJECTIVE: Compare the frequency of NEC in preterm infants receiving probiotics plus conventional therapy in 2012 patients who received conventional therapy in the neonatal unit of the Hospital Vicente Corral Moscoso in 2011. METHODOLOGY: A cohort study with two groups of 113 infants. The intervention group received 1g of probiotics VSL # 3 for 2012 once a day until with a maximum 14 days and during administration were recorded cases of NEC according to Bell's criteria, and compared with frequency presented in 113 preterm ECN 2011. RESULTS: In 2011 there was a 22.1% while those who received probiotics ECN was 10.6%. The groups represented were statistically significant reduction in preterm VLBW infants and moderate (p value <0.05). A smaller percentage (7.5%) of NEC was observed in male infants in relation to women (13.3%) with the administration of VSL # 3. The percentage of NEC was 20% and 25% in male and female respectively receiving no probiotics. CONCLUSIONS: The VSL # 3 probiotic decreased the frequency of NEC in premature neonatal ward of Hospital Vicente Corral Moscoso in 2012 with Relative Risk Reduction (RRR) of 52%