Estudio clínico aleatorizado multicentro de la eficacia analgésica del tramadol durante la fase activa del parto

Abstract

Background: Pain relief is a significant issue for women in labor. The level of pain experienced and efficacy in decreasing pain influence the satisfaction of the mother.

Objective: To determine the efficacy of Tramadol 100mg IM, to decrease the pain of active labor, interference with the duration of the active phase, vitality fetal, neonatal and significant adverse effects.

Methods and techniques: We conducted a multicenter randomized controlled trial, blinded assessor and the statistical results in the “Hospital José Carrasco Arteaga” and “Vicente Corral Moscoso” of Cuenca- Ecuador, from December 2012 to september 2013, the study group was formed 73 parturients to Tramadol were administered during the active phase of labor, and for the control group were given 73 parturients N - butyl scopolamine.

Results: it was found that at 30 minutes and when evaluated with tramadol, the pain was constant, but with the N-butyl scopolamine there was an increase, reaching the latter to be severe at 2 hours, which never happened to manage the Tramadol, even after 4 hours of evaluated, showing that there is a decrease in pain and a constant moderate pain all the time evaluated. Regarding the duration of the active phase, prolongation was not seen in the same, either impaired fetal vitality, but if there was a greater change in the newborn Apgar, which is not clear whether might be attributed to other causes. Regarding adverse effects of matched: nausea and vomiting were higher in the tramadol group without becoming a major contraindication for administration.

Descriptors: ACTIVE PHASE OF LABOR, VISUAL ANALOG SCALE (EVA), TRAMADOL, N - BUTYL SCOPOLAMINE.