Estudio de la influencia de las variables operacionales en la adsorción de fármacos sobre residuos vegetales aplicando diseño experimental multivariante

Abstract

The present titration work is part of the research project presented to the DIUC of the University of Cuenca, which is entitled "Evaluation of emerging pollutants present in Ucubamba wastewater and its elimination by biosorption and phytoremediation, providing the study of the influence of operational variables in the adsorption of drugs on plant residues, applying multivariate experimental design. In the first place, the complete factorial design was developed 23, for three variables or factors to be manipulated, the initial concentration of the drug, temperature and contact time, in turn, the factors were kept fixed. Amount of biomass (according to the drug), pH 6 and Stirring speed at 150 rpm. The mathematical process and the interaction of the factors was carried out in the Minitab® 18 software, to determine an equation that models the adsorption behavior. The results of the experimental design tests are reflected in polynomial equations of simulation of behavior during a process of batch adsorption (batch) with agitation, for each of the biomasses being these, Sugar Cane Bagasse and corn cob, the drugs adsorbed in aqueous solution were Sulfamethoxazole, Ciprofloxacin, Paracetamol and Ibuprofen. The kinetic model and equilibrium were applied, demonstrating that both biomasses are better suited to the kinetic model of Pseudo Second Order and different models of equilibrium isotherms depending on the drug studied, for the Langmuir and Freundlich isotherms.