Factores asociados a hemorragia digestiva alta no variceal en pacientes mayores de 39 años: Hospital Vicente Corral Moscoso, Cuenca, 2012

Abstract

OBJECTIVE: To determine the association between non-variceal upper gastrointestinal bleeding with NSAIDs consumption, alcohol, snuff and personal history of dyspepsia in patients over 39 years, hospitalized in the Department of Internal Medicine Vicente Corral Moscoso during January 2008 to January 2012. MATERIALS AND METHODS: We conducted a case-control study. The sample was calculated based on 95% confidence, power of 80%, OR of 3 and 15% of consumption inflammatory and size formula was applied to cases and controls. Were matched by age and sex, and two controls per case. Data were obtained from medical records and direct interview and analyzed with Epi Info RESULTS: 60.1% were men. The age ranged between 40 and 94 years, the median was 73.0. The groups were similar in mean age and frequency of female and / or male (p> 0.005). Consumption of NSAIDs, snuff and personal history of dyspepsia were are risk factors for upper gastrointestinal bleeding (OR: 2.1, 95% CI 1.2 - 3.6 and p value = 0.006) (OR: 2.0, 95% 1.1 - 3.6 and p value = 0.018) (OR: 22.4, 95% CI 9.2-54.7 and p value = 0.000) respectively. CONCLUSIONS: Consumption of NSAIDs, snuff and personal history of dyspepsia are risk factors for non-variceal upper gastrointestinal bleeding.