Heterogeneidad de genotipos VPH en condiloma acuminado orofaríngeo: reporte de caso procedente de Ecuador

Abstract

Introduction: Condyloma acuminatum (CA) or venereal wart is a viral infection caused by Papillomavirus, acquired primarily through sexual contact; adolescents and young adults are the most vulnerable group to this condition. Its presentation in the oral cavity is atypical, as is its positivity for viral genotypes other than 6, 11, 16 and 18. Clinical case: We present an unusual case of oropharyngeal condyloma in a young adult woman with dyslipidemia and vitamin D deficiency, which showed co-infection with low (HPV-6 and 11) and high oncogenic risk genotypes (HPV-59 and 82). To date, these last two have not been documented in cases of oral or oropharyngeal cancer. The diagnosis of the reported lesion was based on clinical and pathological findings; its prognosis was reserved, given its location. Conclusion: Although the diagnosis of AC is fundamentally clinical, for the oral entity the histopathological findings are key when differentiating it from other oral HPV-mediated entities. Genotyping is not decisive in the diagnosis, having only an epidemiological impact when developing and applying vaccination schedules.