Prevalencia de mortalidad en pacientes infectados con enterobacterias productora de carbapenemasas y factores asociados. Hospital Vicente Corral Moscoso. Cuenca, 2014- 2017.

Abstract

Background: intrahospital Infections, are a public health problem, for the economic cost, and the high mortality. Objective: To determine the prevalence of mortality in patients infected with enterobacteria producing carbapenemase and factors associated. Methodology: It is a transversal analytical study in which all patients diagnosed with infection by carbapenemase producing enterobacteria from 2014 to 2017, and the prevalence of mortality and factors is analyzed. For statistical analysis, the prevalence ratio was used with a IC 95% and a level of significance of p <0.05. Results: the prevalence of mortality is 39.7%, the associated factors for mortality in patients with serious infection are: immunosuppressive treatment (p 0.004), and the Charlson index (p 0.01). In patients with minor infection the associated factors for mortality are: age (p 0.01), hospital stay (p:0.006), previous bacterial infection (p: 0.02), Previous antibiotic treatment (p 0.01), immunosuppressive treatment (p 0.01), comorbidities (p 0.0006), and Charlson index (p 0.000). Conclusions: a high prevalence of mortality due to carbapenemase infections has been found, the associated factor in serious infection are immunosuppressive treatment and Charlson index, and in patients with minor infection age, prolonged hospitalization, previous bacterial infection, previous antibiotic treatment, immunosuppressive treatment, comorbidities, and Charlson index.