Adenocarcinoma pleomórfico de células giganates de vías biliares(osteoclastoma like)

Abstract

Osteoclast-type giant cells (CGTO) of the pancreas are not frequent originally described by Rosaien 1968, characterized by osteoclasts that are giant cells identical mononuclear stromal cells in bone tumors observed. Since then, there are few reports of tumors containing giant cells in other anatomic locations. The CGTO can be distinguished from the pleomorphic type giant cells (CGTP), due to the lack of an associated marked nuclear pleomorphism. Often a pancreatic carcinoma histologically recognizable CGTO accompanies, leading to a bad result. CGTO pure forms have a better prognosis because it takes a long time to develop metastases, but this form is very rare, with few cases reported in the English literature. Most times the benign diagnosis of these tumors based on immunohistochemistry evaluation is discussed. This case is a female patient 56 years old with picture characterized by cramping pain that improves with antispasmodics, several months of evolution, with periods of remission and exacerbation. A physical exam features: light skin and mucous subictérico dye, abdominal level: diffusely painful abdomen without viseromegalias or palpable masses