Proliferación Osteocondromatosa Parostal Bizarra o Enfermedad de Nora revisión de la literatura: a propósito de un caso

Abstract

Bizarre parostal osteochondromatous proliferation (BPOP for its acronym and abbreviation in English) or also called Nora's disease is a rare, benign lesion, whose radiographic characteristics such as cortical widening and corticomedullary continuity of the underlying cortex and histological characteristics such as the socalled “blue bone” can lead to a misdiagnosis. Most of the cases reported in the literature correspond to the small tubular bones of the hands and feet, being the involvement of the skull and jaws extremely rare. The etiology of this disease is not yet well defined and is a matter of controversy, since there are two theories regarding the subject, the first theory mentions that BPOP is part of a reactive mechanism and it is an intermediate phase between florid reactive periostitis and turret exostosis, while the neoplastic theory mentions that BPOP is the product of a genetic abnormality. Treatment is surgical and includes surgical excision, simple resection and resection with wide margins; the lesion presents high recurrence (50%) for this reason, when it occurs in small bones such as metacarpals, total amputation of the bone is chosen. For the correct and definitive diagnosis of BPOP, a meticulous clinical, radiographic and histological analysis will be carried out. Here we present a case of BPOP involving the alveolar ridge of the mandible of a 72-year-old woman. This would be the ninth published case of bizarre parostal osteochondromatous proliferation corresponding to the maxillofacial region and the fifth case located in the mandible.