Browsing by Author "Tamayo Zambrano, Andrea Pavlova"

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    Evaluación de la calprotectina fecal como biomarcador en el diagnóstico de la Enfermedad Inflamatoria Intestinal en perros de la ciudad de Cuenca
    (Universidad de Cuenca. Facultad de Ciencias Agropecuarias, 2026-02-12) Ayala Méndez, Emily Yairis; Tamayo Zambrano, Andrea Pavlova; Picón Saavedra, Marco Antonio
    Inflammatory bowel disease (IBD) in dogs is a chronic condition with gastrointestinal manifestations, characterized by chronic diarrhea, as well as other signs that may include vomiting, weight loss, and abdominal pain. Definitive diagnosis is based on histopathological examination of the affected tissue, an invasive and costly procedure. Therefore, this study evaluated the usefulness of fecal calprotectin as a non-invasive biomarker for the diagnosis of IBD in dogs in the city of Cuenca, Ecuador. Thirty-six patients were analyzed, divided into three groups of 12 dogs each: healthy dogs, dogs with acute diarrhea, and dogs with IBD confirmed by histopathology. Fecal calprotectin levels were measured using ELISA. The results revealed significant differences between the groups (p < 0.05). In Tukey´s test, we observed two homogeneous subsets shared by healthy patients and those with acute diarrhea, with values significantly lower than those of the second subset, which corresponds to patients with IBD. These findings support the effectiveness of using fecal calprotectin as a biomarker to differentiate IBD from other gastrointestinal pathologies.