Browsing by Author "Sánchez Artigas, Rolando"

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Efficacy of a lupinus mutabilis sweet snack as complement to conventional type 2 diabetes mellitus treatment
(2019) Fornasini Salvador, Marco Vinicio; Abril Ulloa, Sandra Victoria; Beltran Carreño, Jose Patricio; Villacrés, Elena; Cuadrado Merino, Lourdes Flora; Robalino Buenaño, Jesus Francisco; Sánchez Artigas, Rolando; Ricaurte Ortiz, Paul Stalin; Muñoz, Erika; Benitez Loza, Napoleon Benjamin; Baldeón, Manuel E.
Introduction: therapeutic lifestyles changes including frequent consumption of legumes have resulted in improved metabolic control and decreased blood pressure in type 2 diabetes-mellitus (T2DM) patients. Objective: this was a quasi-experimental-28-week crossover-study that assessed the effect of daily consumption of the legume Lupinus mutabilis (LM) on metabolic control of T2DM patients under hypoglycemic oral treatment. Material and methods: we recruited 79 adult male and female patients that were followed for 14-weeks without LM consumption and then received increasing doses of a LM-based-snack for other 14-weeks. Results: there was a significant decrease in blood pressure and a significant increase in HDL-cholesterol after LM consumption. While patients with A1C concentrations > 8 and ≤ 10 did not significantly improve their metabolic control, patients with serum A1C concentrations ≤ 8.0% reduced significantly their A1C after the intervention and 71% achieved a target concentration of 6.5%. Conclusion: patients with T2DM could benefit with the addition of LMsnack to their conventional treatment.