Browsing by Author "Quizhpi Buestan, Micaela Abigail"

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    Influencia hemodinámica de la xilacina y dexmedetomidina en perros sometidos a orquiectomías
    (Universidad de Cuenca. Facultad de Ciencias Agropecuarias, 2026-02-12) Narváez Carangui, Lissbeth Katherine; Quizhpi Buestan, Micaela Abigail; Solano León, María Katherine
    Anesthetic safety in veterinary medicine depends on maintaining the anesthetic triad: hypnosis, pain relief (analgesia), and muscle relaxation. While alpha-2 adrenergic agonists are widely used in premedication for their strong sedative and pain-relieving effects, their impact on blood flow stability (hemodynamics) requires careful monitoring. This experimental study took place at the Veterinary Teaching Clinic of the University of Cuenca. The goal was to evaluate the physical changes caused by two drugs from this family. A random sample of 40 dogs (n = 40) scheduled for orchiectomy (neutering) was selected and divided into two groups: Group 1 (G1) received premedication with xylazine, while Group 2 (G2) received dexmedetomidine. The protocol includes continuous monitoring of vital signs: heart rate, breathing rate, capillary refill time, and blood pressure. This was done during the preoperative, intraoperative, and postoperative phases. Statistical analysis revealed that there was no significant difference (p = >0, 05) between the use of xylazine and dexmedetomidine regarding physiological stability in any of the three phases. Additionally, the Pearson correlation test showed that factors like age and weight had a very low negative relationship with the physical results, and this was not statistically significant (p = >0,05). In conclusion, both drugs offer a similar safety profile for maintaining body balance (homeostasis) during orchiectomy in healthy dogs.