Browsing by Author "Pinos Gavilanes, Maria Paz"

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A systematic review on modulation of oral biofilm and immune response associated to mucosa with probiotic bacteria as a potential approach in the prevention of dental caries
(BP Internacional, 2021) Rodríguez Coyago, María de Lourdes; Buestan Zambrano, Juan Fernando; Yamunaque Vire, Jessica Micaela; Pinos Gavilanes, Maria Paz; Osorio Ayala, Lesly Damaris
Background: A variety of approaches have been developed for the control of dental caries, a pathology with high incidence and prevalence worldwide. The use of probiotic strains for the modulation of dental biofilm in the prevention of caries has been studied, but the available evidence shows varied methodologies; and the strains tested differ from one study to another. Objective: To analyze the efficacy of using probiotic strains to prevent caries through the modulation of biofilm and immune response associated to oral mucosa. Methods: A search was made in the scientific bases PubMed, Cochrane and Science Direct, prioritizing randomized double and triple-blind clinical trials from 2010 to 2020, including a total of 20 studies to be analyzed. The selection criteria were consistent with the Preferred Reporting Items for Systematic Reviews protocol. Results: Within the studies, different types of probiotic bacteria were analyzed, dominating Lactobacillus paracasei. While most clinical trials show a favorable response in terms of a significant reduction of Streptococcus mutans in the oral microbiota, very few studies evaluated salivary pH and sIgA levels. Conclusions: The heterogeneity of the studies analyzed and the multifactorial nature of dental caries do not allow us to ensure that probiotic therapy is completely effective in preventing this pathology. Although probiotic therapy can help by regulating the microbiological factor, there are other determinants that can favor the development of caries and that are barely approached in their relationship with bacteriotherapy. Future studies that homogeneously evaluate the use of probiotics could give us a clearer idea of their effectiveness
Actinic cheilitis: clinical, pathological and therapeutic considerations
(2021) Bravo Calderón, Diego Mauricio; Pinos Gavilanes, Maria Paz; Pinos Gavilanes, Daniel Esteban
Actinic cheilitis (AC) is a chronic inflammation that affects more frequently to the lower lip and is considered as a potentially malignant disorder that could develop in to squamous cell carcinoma (SCC). AC is caused by excessive exposure to ultraviolet (UV) radiation, mainly sunlight radiation. Fair-skinned male patients, older than 50 years, who have worked outdoors or have had long-term sunlight exposure are more susceptible to develop this lesion. Their clinical manifestations are very varied; nevertheless, they are not related to the histopathological alterations that can be found. Histopathological diagnosis is the most important predictive factor of malignant transformation, depending on the severity of epithelial dysplasia. The characteristics of the AC are reviewed, so the clinician can provide optimal care to the patient and prevent lip cancer. The literature review was performed analyzing articles from PubMed, Science Direct, Google Scholar and Cochrane databases.
Afecta el Síndrome de la Respiración Bucal el crecimiento general y desarrollo cognitivo de niños y adolescentes?: Revisión de la literatura
(2020) Quito Zhinin, Andrea Elizabeth; Barzallo Sardi, Vinicio Egidio; Yunga Picon, Maria Yolanda; Sarmiento Aguilar, Cristina Paulette; Pinos Gavilanes, Maria Paz
Abstract Mouth breathing syndrome has several health consequences, especially in children and adolescents. The objective of the present study was to carry out a literature review to identify the alterations and consequences associated with mouth breathing syndrome. The search for articles was performed in electronic databases including: PubMed, Elsevier, EBSCO, Medline, SCielo, Springer; The keywords used were: “mouth breathing”, “children”, “body growth”, “maxillary growth”, “cognitive development”; articles in English from the last 10 years were included, a total of 26 articles were included in this Review. Most of the children and adolescents with mouth breathing showed alterations in the corporal posture with hyperextension of the head acquiring kyphosis posture and therefore intervening in the development and craniofacial growth, showing a greater inclination of the jaw and greater anterior height facial, in addition to presenting some class II malocclusions, posterior crossbite and anterior open bite. In addition to physical changes, their cognitive development was also affected in patients with oral respiration, with early recognition and timely treatment are essential to improve the quality of life of these patients.
Eficacia de la bacterioterapia probiótica para la prevención de caries dental: una revisión sistemática de la literatura
(2020) Osorio Ayala, Lesly Damaris
Background: A variety of approaches have been developed for the control of dental caries, a pathology with high incidence and prevalence worldwide. The use of probiotic strains for the modulation of dental biofilm in the prevention of caries has been studied, but the available evidence shows varied methodologies; and the strains tested differ from one study to another. Objective: To analyze through a systematic review of clinical trials, the efficacy of using probiotic strains to prevent dental caries. Methods: A search was made in the scientific bases PubMed, Cochrane and Science Direct, prioritizing randomized double and triple-blind clinical trials from 2010 to 2020, including a total of 20 studies to be analyzed. The selection criteria were consistent with the Preferred Reporting Items for Systematic Reviews protocol. Results: Within the studies, different types of probiotic bacteria were analyzed, dominating Lactobacillus Paracasei. While most clinical trials show a favorable response in terms of a significant reduction of Streptococcus mutans in the oral microbiota, very few studies evaluated salivary pH and sIgA levels. Conclusions: The heterogeneity of the studies analyzed and the multifactorial nature of dental caries do not allow us to ensure that probiotic therapy is completely effective in preventing this pathology. Although probiotic therapy can help by regulating the microbiological factor, there are other determinants that can favor the development of caries and that are barely approached in their relationship with bacteriotherapy. Future studies that homogeneously evaluate the use of probiotics could give us a clearer idea of their effectiveness.
Modulation of oral biofilm and immune response associated to mucosa with probiotic bacteria as a potential approach in the prevention of dental caries: a systematic review
(2020) Osorio Ayala, Lesly Damaris; Buestan Zambrano, Juan Fernando; Yamunaque Vire, Jessica Micaela; Pinos Gavilanes, Maria Paz; Rodriguez Coyago, Maria De lourdes
Background: A variety of approaches have been developed for the control of dental caries, a pathology with high incidence and prevalence worldwide. The use of probiotic strains for the modulation of dental biofilm in the prevention of caries has been studied, but the available evidence shows varied methodologies; and the strains tested differ from one study to another. Objective: To analyse through a systematic review of clinical trials, the efficacy of using probiotic strains to prevent dental caries. Methods: A search was made in the scientific bases PubMed, Cochrane and Science Direct, prioritizing randomized double and triple-blind clinical trials from 2010 to 2020, including a total of 20 studies to be analysed. The selection criteria were consistent with the Preferred Reporting Items for Systematic Reviews protocol. Results: Within the studies, different types of probiotic bacteria were analysed, dominating Lactobacillus Paracasei. While most clinical trials show a favorable response in terms of a significant reduction of Streptococcus mutans in the oral microbiota, very few studies evaluated salivary pH and sIgA levels. Conclusion: The heterogeneity of the studies analysed and the multifactorial nature of dental caries do not allow us to ensure that probiotic therapy is completely effective in preventing this pathology. Although probiotic therapy can help by regulating the microbiological factor, there are other determinants that can favor the development of caries and that are barely approached in their relationship with bacteriotherapy. Future studies that homogeneously evaluate the use of probiotics could give us a clearer idea of their effectiveness.