Browsing by Author "Peralta Avila, Andrea Nicole"

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    La Porphyromonas gingivalis como vínculo entre la periodontitis y la enfermedad de Alzheimer. Revisión narrativa de literatura
    (Universidad de Cuenca, 2023-10-04) Peralta Avila, Andrea Nicole; Carvajal Endara, Andrea Soledad
    Alzheimer's disease (AD) is one of the most common neurodegenerative disorders in the world and has been listed as a global public health priority by the WHO. There is currently no effective treatment for the disease and its cause is still unknown. In recent years, attempts have been made to explain the etiological mechanisms of AD, one proposed hypothesis is the spread of oral microorganisms such as Porphyromonas gingivalis (Pg) to brain tissue in patients with periodontitis. However, this possible causal relationship remains unclear. Objective: to present the role of Pg as a link between periodontitis and Alzheimer's disease based on a literature review of publications from the last 5 years. Materials and methods: search of publications in the following databases: PubMed, SpringerLink, Scientific Direct, Scielo. Results: 19 scientific articles were included of which animal and molecular studies determine that, Pg infection increased the production of inflammatory mediators, thus causing an increase in the production of Aβ (beta amyloid) and subsequently, neurodegeneration compatible with AD; however, no clear relationship has been established in human studies. Conclusion: the effect of Pg on the development of neuroinflammation has been demonstrated; however, further large-scale studies and longitudinal follow-up in humans are needed to better establish the relationship between periodontitis and AD.
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    Status of light power intensity of light curing lamps in private dentalclinics in ciudad de Cuenca, Ecuador
    (2023) Bravo Calderón, Manuel Estuardo; Bravo Lozano, Ariana Lucia; Peralta Avila, Andrea Nicole; Lima Tola, Esteban Fernando
    The clinical efficiency of a photo polymerization unit is crucial to obtain an optimal polymerization and a successful result. The present observational study aimed to evaluate and analyze the intensity of the luminous power of the photo polymerization lamps of private dental clinics in Cuenca City, Ecuador.The luminous intensity was evaluated using the CK12024 radiometer (measured the curing time up to2000). It was classified according to the following parameters: Low performance (<300mw/cm2),regular performance (300 – 800 mw/cm2) and high performance (>800 mw/cm2), in a time of 20seconds and 40 seconds. in “Microsoft Excel”,;to register all the necessary data: number of lamp, typeof lamp, intensity of light power in 20 seconds, intensity of light power in 40 seconds, breakage of optical fiber and residues of biomaterials in the optical fiber. If you obtained as a result that of the 58lamps evaluated, a percentage of 0.6% (n=1) of the total photo polymerization units had a low performance, a 5.2% (n=3) had a medium performance and a 93.1% (n = 54) of them had a high performance. An adequate polymerization is crucial to obtain good physical and mechanical properties and excellent clinical results. According to the results obtained within the present study, it is observed that the majority of the photo polymerization lamps used in the private offices of the City of Cuenca, have a high clinical performance.