Browsing by Author "Ortiz Sibri, Janneth Cristina"

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    Eficacia farmacológica de la infusión intramamaria de agentes antimicrobianos (bactericidas y bacteriostáticos) en el período de secado
    (Universidad de Cuenca, 2025-08-06) Ortiz Sibri, Janneth Cristina; Pulgarín Macas, Daniela Jacqueline; Narváez Terán, Jhonny Alfredo
    Subclinical mastitis is one of the main causes of economic losses in dairy production, due to its negative effect on reduced milk production and increased veterinary expenses. The objective of this study is to evaluate the efficacy of bactericidal (cloxacillin) and bacteriostatic (lincomycin) antimicrobial agents by intramammary infusion in the elimination of subclinical infections during the dry-off period. Sixty mammary quarters from cows diagnosed with subclinical mastitis were analyzed at two points in time (first 15 days of the dry-off period and 7 days postpartum). Among the bacteria identified in the samples were Escherichia coli (23.33%), Staphylococcus spp. and Streptococcus spp. (85% together), in addition to Gram-positive (3.34%) and Gram-negative (5%) bacilli. In terms of antimicrobial sensitivity, cloxacillin showed 40% sensitivity against the isolated strains, while lincomycin reached 36.67%. Cloxacillin was more effective against Staphylococcus spp. than lincomycin (34.38%), while lincomycin showed better results against Streptococcus spp. (28.57%). Likewise, both drugs achieved 100% efficacy against Escherichia coli. However, both treatments showed limited efficacy against Gram-positive bacilli. These results suggest that the use of bactericidal antimicrobials during drying offers better results in the prevention and control of bacterial infections.