Browsing by Author "Murillo Sotomayor, Kevin Eduardo"

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    Evaluación de la adherencia a la terapia farmacológica psiquiátrica en pacientes con trastornos depresivos atendidos en un consultorio privado de la ciudad de Loja-Ecuador
    (Universidad de Cuenca, 2025-09-25) Murillo Sotomayor, Kevin Eduardo; Ochoa Castro, Maritza Raphaela
    Depressive disorders are one of the leading causes of morbidity and mortality worldwide, with significant repercussions on psychosocial functionality and health systems. Suboptimal adherence to antidepressant pharmacological treatment poses a clinical challenge, as it compromises therapeutic efficacy and increases the risk of recurrence and suicide. Therefore, the present study aimed to evaluate adherence to psychiatric pharmacological therapy in patients with depressive disorders treated in a private clinic in the city of Loja, Ecuador. A quantitative approach was used with a non-experimental, descriptive, and cross-sectional design. Data collection was carried out using a structured survey and three validated scales: medication adherence, side effects (UKU), and quality of life for depression (QLDS). The statistical analysis performed with the R software included Fisher’s exact tests, ANOVA, and Tukey HSD post hoc analysis. The results showed a high prevalence of depression in young women with a higher level of education. Adherence was predominantly moderate, with significantly lower levels in those under 30 years old (p < 0.001). Furthermore, a statistically significant association was found globally between side effects and the level of adherence (p = 0.00165), as well as social support and psychotherapy positively correlated with better quality of life. It is concluded that it is essential to implement interventions aimed at young people, focused on the comprehensive management of adverse effects to improve therapeutic adherence.