Browsing by Author "Murillo Bacilio, Magdali Del rocio"

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    Intraepithelial cervical lesions in indigenous in Ecuador
    (2019) Salazar Torres, Zoila Katherine; Murillo Bacilio, Magdali Del rocio; Castro Reyes, Boris Santiago; Cardenas Heredia, Freddy Rosendo; Sanchez Salazar, Gustavo Mauricio
    The aim of this research was to determine the prevalence of cervical intraepithelial lesions in indigenous women of Ecuador 2017. A descriptive study was performed. Population was formed by 2489 indigenous women aged 15 to 64 years old, of which 396 users were chosen by spontaneous demand. Frequency values and percentages were taken from qualitative variables, while mean and standard deviation were taken from quantitative variables. Prevalence of intraepithelial lesions was 13,8%. Average age was 31 years old. Uncertain importance's squamous atypical cells were higher in 30-to-39-year-old group (46,7%). Non-specific atypical glandular cells were observed in 66,7% of 30-to-39-year-old group. Low-grade intraepithelial lesions were majorly found in 20-to-29-year-old group (43,8%). High-grade intraepithelial lesions were also seen in 20-to-29-year-old group. Conclusions were: prevalence of intraepithelial lesions in indigenous women of Ecuador was higher than 10% of reported in other studies, and more frequent in those aged 20 and 39 years old.
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    Predictive equation of metastasis in patients with malignant ovarian epithelial tumors with the Ca-125 marker
    (2018) Sanchez Vega, Juan Fernando; Murillo Bacilio, Magdali Del rocio; Vintimilla Condoy, Adrian Santiago; Palta Gonzalez, Araceli Miroslava; Crespo Astudillo, Jose Alfredo; Mora Bravo, Franklin Geovany
    Background: Cancer antigen (CA) 125 (CA-125) is used in ovarian cancer detection and monitoring, whose serum level has a positive correlation with tumor stage. The aim of this study was to obtain a prediction metastasis equation in a group of patients with ovarian cancer based on Ca-125. Methods: A 2-group comparative observational study was conducted at a single oncologic institution (SOLCA) in Cuenca-Ecuador. All patients who were diagnosed with ovarian cancer between January 1996 and December 2016 were included in the current study. Group 1 (G1) patients with the I and II International Federation of Gynecology and Obstetrics (FIGO) stage and Metastasis Group (MG), with III and IV stage, were subdivided. A logistic regression equation was performed to predict metastasis based on Logarithm of serum Ca-125 levels. Results: We included 85 cases in G1 and 64 patients in MG, with 47.8 plusmn; 15 years (G1) and 57.5 ± 13.6 years (MG) of age (P < 0.001). Mortality in G1 was 2 cases (3.1%) and 53 cases (62.4%) in MG (P < 0.001). The CA-125 serum level was 163.5 ± 236 in G1 and 1220.9 ± 1940 u / ml in MG (P < 0.001). The equation to predict metastasis = (Age*0.053) + [(Logarithm Ca-125 value) * 1.078] -8.163 with an OR 2.940 (CI 95% 2.046-4.223) P < 0.001. The sensitivity of the equation was 82.4% and the specificity was 79.7%. Conclusions: It is possible to predict the presence of metastasis in a group of patients with ovarian cancer based on Ca-125. © 2018 The Author(s).