Browsing by Author "Idrovo Macancela, Mayra Estefania"

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    Anemia asociada a la inflamación: prevalencia y factores asociados en pacientes ingresados en el Hospital Vicente Corral Moscoso Cuenca 2021
    (Universidad de Cuenca, 2023-07-21) Idrovo Macancela, Mayra Estefania; Dita Salabert, Liermis Michael
    Introduction: Inflammatory Anemia (IA) is the impaired production of erythrocytes associated with chronic immune activation, it is mainly a disorder of iron distribution and the second cause of anemia in the world.Objectives: to determine the prevalence of anemia due to inflammation and its associated factors in patients admitted to the Vicente Corral Moscoso Hospital (HVCM) during the year 2021.Methodology: A cross-sectional analytical study was carried out in a sample of 440 patients hospitalized in the Internal Medicine area of the HVCM, the sample calculation was performed with 95% confidence, 50% probability of occurrence and 4.2% error, for data collection, a form designed and prepared by the author was applied, for the analysis the Chi Square was applied for association between variables and OR to measure the intensity of association, with a significance level of 5% (p<0.05 ), processing performed in the SPSS V27.Results: a prevalence of IA of 18.18% was found in all hospitalized patients. Associated factors were: age (p=0.018); diabetes (p=0.003), infection (p=0.001) and chronic kidney disease (p=0.025). The presence of IA was not related to mortality in this study. Conclusions: the prevalence of IA was 18.18% and is mainly associated with the age of the patients and the presence of chronic diseases such as diabetes mellitus, infections and chronic kidney disease.
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    Factores clínicos gastrointestinales como expresión fenotípica de COVID-19. Revisión bibliográfica
    (2022) Torres Arevalo, Janina Tatiana
    Introduction: the appearance of the new Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) or Coronavirus Disease 2019 (COVID-19) and its rapid spread, caused a worldwide health emergency. This virus mainly affects the respiratory system, but also the gastrointestinal tract.Objective: to identify if the secondary gastrointestinal manifestations to COVID-19 infection are an important phenotypic expression of this pathology.Methodology: a systematic search was carried out in scientific medical journals in the databases: Scielo, PubMed, SpringerLink, Wiley Online Library, Scopus with the following terms “Gastrointestinal manifestations due to COVID-19”, “Gastrointestinal symptoms due to SARS-CoV2”, “Gastrointestinal alterations in COVID-19”, published in English and Spanish between 2020 and 2021.Results: the most frequent gastrointestinal symptoms were diarrhea, nausea, vomiting, anorexia and abdominal pain. The physiopathology of gastrointestinal manifestations depends on angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2). The detection of viral RNA in feces as a diagnosis has been detected in 53.4% of infected patients, other methods described are not definitive. Finally, the treatment of gastrointestinal manifestations due to COVID-19 is symptomatic.Conclusions: the advances in the epidemiology, pathogenesis, clinical characteristics, means of diagnosis and treatment of COVID-19, show that secondary gastrointestinal manifestations occur in a manner and frequency variable, allowing to face this epidemic disease more effectively.