Browsing by Author "Hurtado Matute, Johanna Alexandra"

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Mortalidad y su relación con el estado nutricional en pacientes críticos en la Unidad de Cuidados Intensivos del Hospital Vicente Corral Moscoso de octubre 2021 a enero del 2022, Cuenca Ecuador
(Universidad de Cuenca, 2024-01-02) Hurtado Matute, Johanna Alexandra; Aguirre Bermeo, Hernán Marcelo
Background: Malnutrition in critically ill patients has gained importance; studies have shown that obesity and malnutrition are independent risk factors for mortality, leading to a longer stay in intensive care and time on mechanical ventilation. In our country there is no data on malnutrition in critically ill patients or any relationship with mortality. Objective: Determine mortality and its relationship with nutritional status in patients in the Intensive Care Unit of the Vicente Corral Moscoso Hospital from October 2021 to January 2022. Methodology: Analytical, prospective observational study, clinical records were reviewed collecting sociodemographic data, biochemical and anthropometric parameters, arm and calf circumference. Measures of central tendency and dispersion were calculated, Chi2 to measure association, relative risk, 95% confidence interval and p value (< 0.05) for statistical significance. Results: 81 patients, 46% aged between 20 and 44 years, 67% male, 85.2% with enteral nutrition,21% died. 43% of adults were overweight, 52% of older adults had a normal BMI, 46.9% had a moderate risk of malnutrition according to CONUT. Albumin values were lower at discharge, in deceased patients (2.39 mg/dl) and in living patients (2.83 mg/dl) (P= 0.019). Those malnourished according to calf circumference had higher mortality (P=0.030) with a RR 3.68 95% CI (1.08-12.5). Conclusions: There is a high percentage of overweight with a higher risk of death, there was no relationship between anthropometric or biochemical variables at admission, at discharge there was a relationship between mortality with albumin levels and malnutrition according to calf circumference.
Neurodesarrollo en el hipotiroidismo congénito y sus particularidades electroencefalográficas
(Universidad de Cuenca. Facultad de Ciencias Médicas, 2016-12) Calle Ulloa, Boris Eduardo; Calle Saquipay, Ángel Domingo; Hurtado Matute, Johanna Alexandra; Cobos Castro, Johanna Elizabeth; Pinos Brito, María Carmen
Congenital hypothyroidism (CH) is a result of a deficiency of thyroid hormone (TH) by altering thyroid (primary hypothyroidism), or pituitary causes (secondary hypothyroidism) or hypothalamic (tertiary hypothyroidism). Thyroid hormone at the tissue level, is involved in the maturation and functional differentiation of various organs such as the development of the central nervous system (CNS), in which an insufficient supply of HT in time and place, resulting in permanent abnormalities, history highlighting the irreversible intellectual deficit. In the world’s population it has been estimated a frequency of 1: 300 to 1: 4000 newborns. The treatment is oral supplementation with thyroxin. OBJECTIVE: To describe the neurodevelopmental congenital hypothyroidism and electroencephalographic characteristics. MATERIALS AND METHOD: It is an observational, descriptive and cross-sectional study in preschool children diagnosed with HC, who were administered the Denver II scale, a comprehensive neurological evaluation and a digital electroencephalogram. RESULTS: A total of 12 patients, 7 (58%) female and 5 (42%) males were evaluated. All patients were evaluated by the scale of Denver II, 4 (33%) were delayed in their psychomotor development, predominantly in the language area. Regarding the neuro-pediatric assessment was found that 5 patients had neurological manifestations and perform digital electroencephalogram 7 (59%) had electroencephalographic changes, 5 (71%) showed immaturity and 2 (29%) dysfunction. CONCLUSIONS: Afer the analysis made throughout this investigation, the conclusions are: The results of this study show a heterogeneous pattern, however target the possible association between clinical manifestations and electroencephalographic findings. Patients with congenital hypothyroidism present a condition in the area of language which was determined by applying the scale Denver II. The abnormal clinical manifestations are mainly in the verbal area, but they are also presented as subtle manifestations or unspecific as inattention, irritability and behavioral disorders. Keywords: Congenital Hypothyroidism, Neurodevelopmental Disorders, Neurologic Manifestations, electroencephalography