Browsing by Author "Guerrero Altamirano, Eddy Francisco"

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Cáncer de mama triple negativo con sus características mamográficas y ecográficas, y factores asociados. SOLCA-Cuenca 2009-2016
(2019) Amores Grandes, Alberto Israel; Guerrero Altamirano, Eddy Francisco; Beltrán Carreño, José Patricio
Background. The worldwide incidence of breast cancer in 2012 was 1'671.149. Triple negative breast cancer is a distinctive subset of breast cancer that the receptor and hormone receptor unit (HER2). It constitutes 11% to 20% of all breast cancers. Objective. To determine the prevalence of triple negative breast cancer with its mammographic and ultrasound characteristics and its relationship with associated factors in the Cancer Institute SOLCA-Cuenca. Period October 2009-December 2016. Methodology and materials: A cross-sectional analytical study was carried out in 633 patients who met the inclusion criteria. The prevalence of the Triple negative subtype was determined, the mammographic and ultrasound characteristics were identified, and its frequency was related to the associated factors. The analysis of the data was done using the data package with descriptive statistics SPSS version 20. Results: The prevalence of triple negative breast cancer was 13.11%. The most frequent mammographic presentation findings were the presence of an oval hyperdense nodule with darkened or microlobulated margins. In ultrasound, they were preferably hypoechoic nodules with an oval or irregular shape, microlobulated margins, with posterior acoustic reinforcement and annular vascularity. Having 3 or more children constituted a risk factor (PR: 1.59). Women who are overweight or obese may be less likely to acquire a tumor of this subtype (PR: 0.91). Conclusions: Triple negative breast cancer usually has common mammographic and echographic characteristics that could suggest its diagnosis. Associated factors such as parity and overweight can relate differently to this cancer subtype.
Cáncer de Mama y su asociación con la densidad mamaria Incrementada, visualizada por Mamografía en el Instituto del Cáncer Solca. Cuenca 2013 – 2015
(2019) Mina Romero, Elizabeth Del Carmen; Guerrero Altamirano, Eddy Francisco; Beltrán Carreño, José Patricio
Background: Currently, breast cancer is the second most common type of cancer in the world, representing the fifth cause of cancer death. In Ecuador in 2012 it ranked first in incidence with 2298 cases and the third place as cause of death. Objectives: To determine the association between breast cancer and increased mammary density visualized by mammography, in women between 45 and 70 years old, at the Cancer Institute SOLCA Cuenca between January 2013 and December 2015. Method and technique: A retrospective study of cases and controls was carried out. The mammographic plates of patients diagnosed with breast cancer confirmed by histopathological study and of patients without breast cancer were analyzed to determine the mammary pattern according to the current classification of BIRADS, at the Cancer Institute SOLCA-Cuenca, period 2013-2015 . The statistical relationship between high-risk mammary density (C and D) and breast cancer was established. Radiological findings were also analyzed and described in all cases and controls. Results: The average age was 55.31 years ± 7.62. The main mammographic findings in the cases were the presence of irregular, hyperdense and spiculated nodules; focal asymmetry, architecture distortion, pleomorphic fine calcifications of grouped distribution, cutaneous thickening and ganglia of suspicious morphology. Mammary density C and D increased the risk of developing breast cancer OR 8.58 (IC 3.5 – 20.60 p=0.000). Conclusion: Mammary density C and D increases the risk of breast cancer
Determinación de sintomáticos respiratorios como fase previa al dignóstico de tuberculosis en la población Shuar-Cantón Morona Provincia de Morona Santiago 1989-1990
(1991) Guerrero Altamirano, Eddy Francisco; González Zeas, Estebán Santiago; Fernández de Córdova Jerves, Ricardo Alfredo; González V., Francisco; Bermúdez Rebolledo, Miguel Ángel; Andino Vélez, José Gerardo
Resonancia magnética mamaria en la valoración y etapificación preoperatoria en pacientes diagnosticadas de cáncer de mama en SOLCA, Cuenca, 2016- 2019
(Universidad de Cuenca, 2023-04-25) Suárez Morquecho, Karla Priscilla; Guerrero Altamirano, Eddy Francisco
Background: breast cancer represents the most frequent neoplasia among women worldwide. Breast Magnetic Resonance is an imaging study with enormous value in diagnosis, staging, and treatment, being a tool that provides information on tumor size, degree of local extension, multifocality, multicentricity, bilaterality, among others, many times not provided by other imaging studies. Objective: to describe the findings of Breast Magnetic Resonance in the assessment and preoperative staging in patients diagnosed with breast cancer SOLCA, Cuenca, 2016-2019. Methods: quantitative, observational, descriptive and retrospective study with 131 patients with breast cancer. Medical records were reviewed and the different variables were recorded using a form. Statistical analysis was performed using the SPSS 15 program, the results were presented using frequencies, percentages, mean, standard deviation, asymmetry, kurtosis, and the Kolmogórov-Smirnov test. Results: Average age was 47 years, 54.20% were married. The most frequent level of education was secondary (33.59%), the majority had urban residence (90.08%) 57.26% were multiparous, 57.25% had exposure to hormonal contraceptives, and 19.08% had a family history of breast cancer. The most frequent histological type was ductal carcinoma (78.63%) and molecular type Luminal B (41.98%) 87.79% had BI-RADS VI classification. The most frequent imaging finding was malignant-looking axillary lymph nodes (30.53%). 30.53% underwent total mastectomy. Change in therapeutic attitude was 41.98%. Conclusions: MRI determines additional findings more frequently in ductal and lobular carcinoma and allows adequate preoperative planning.
Validación y correlación de la tomosíntesis para el diagnóstico de lesiones sospechosas de cáncer de mama en mujeres. Sociedad de lucha contra el cáncer. Cuenca, 2018 - 2019
(Universidad de Cuenca, 2021-06-14) Muñoz Calderón, María Belén; Guerrero Altamirano, Eddy Francisco; Beltrán Carreño, José Patricio
Background: The "Gold standard" for breast pathology is digital mammography, it identifies different types of breast cancers before they have a clinical presentation and thus increase overall survival. Due to its excessive false positive results, it was necessary to implement new diagnostic techniques for the determination of pathology. Objective: To determine the validity and diagnostic correlation of tomosynthesis vs. histopathology in women with suspicious breast cancer lesions. SOLCA- Cuenca 2018 - 2019. Methodology: Validation diagnostic test study that will compare tomosynthesis in lesions suspected of breast pathology with the histopathological result. The universe was made up of 306 women. The sample size will be calculated using the Epidat 3.6 program, with the following criteria: 90% sensitivity, 79% specificity prevalence of the presence of breast cancer 29%, 5% precision, 95% confidence level. Results: tomosynthesis presented a sensitivity of 79.62% and a specificity of 7.58%, indicating that this is the probability that the test will identify the person who is sick as not sick. Conclusions: It was determined that tomosynthesis is a test with little agreement between the result and the histopathological diagnosis.
Validez y concordancia de la mamografía y ecografía en el diagnóstico de Cáncer de Mama de las pacientes atendidas en el Instituto de Cáncer SOLCA Cuenca 2014-2016
(2018) Cabrera Orellana, Karen Silvana; Guerrero Altamirano, Eddy Francisco
Background: the breast cancer is the more frequent neoplasm in women worldwide. Mammography and ultrasound are efficient diagnostic techniques for breast cancer detections and the histology leads to its definitive diagnostic. Objectives: determinate the validity and concordance of the mammography and ultrasound with the histopathology in the breast cancer detection of the attended patients in Instituto de Cancer SOLCA between january 2014 – december 2016. Methodology: validity study and concordance of the diagnostic test conformed by two groups: 79 women with benign pathology and 109 with malign pathology; who presented mammography, ultrasound and histopathology of core biopsy. The results obtained are the statistical indicator of diagnostic validity and concordance. Results: the average age was 53,20 years with a DS of 12,24, the 11,2 % show family history of breast cancer, the 8% were nulliparous and the 4,03% had hormonal replacement therapy. The mammography sensibility was 97,21% and the specificity 53,74% and for the ultrasound was 96,81% and 16,69 respectively. The mammography and ultrasound sensibility together is 99,91% y and the specificity is 8,97%. The ultrasound concordance has a kappa rating of 0,129 and the mammography of 0,46