Browsing by Author "Córdova López, Patricio Fernando"

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Características clínicas-epidemiológicas. Pacientes hospitalizados por meningitis bacteriana. Área de clínica. Hospital José Carrasco Arteaga. Periodo 2014-2019
(Universidad de Cuenca, 2020-11-10) Heredia Sánchez, Erik Antonio; López López, Luis Ángel; Córdova López, Patricio Fernando
Background: despite the arrival of effective antibiotics, mortality from bacterial meningitis remains significant. Previous studies show that the clinical characteristics directly influence the timely recognition and management of this pathology, in Ecuador there are no current clinical data, due to the mainly pediatric approach of the studies. General objective: to determine clinical-epidemiological characteristics of patients with bacterial meningitis in the clinical area, during the period from January 2014 to December 2019. Materials and methods: descriptive study; Universe made up of clinical histories of patients older than 18 years diagnosed with bacterial meningitis in the hospital José Carrasco Arteaga. Results: the study included 66 patients; whose mean age was 54 years. The main symptoms were headache 89.4%, confusional syndrome 86.4% and neck stiffness 84.8%. The causative agent was not identified in 59.09% of patients and the most frequently isolated germs were Klebsiella pneumoniae (13.63%) and Pseudomonas aeruginosa (7.6%). Mortality was estimated at 48.48%. Conclusion: Bacterial meningitis occurred more frequently in patients undergoing surgery and with skull-brain trauma. Clinical characteristics, similar to those reported internationally, occur less frequently than is commonly believed. For this reason, lumbar puncture is essential. However, the causative germ was poorly identified, so, take into account the clinical, blood analysis and imaging studies for timely diagnosis and treatment.
Prevalencia del deterioro cognitivo y factores de riesgo asociados en residentes adultos mayores del Hogar Cristo Rey de la ciudad de Cuenca. 2023
(Universidad de Cuenca, 2024-06-26) Aguirre Collahuazo, Esteban Fernando; Aguilar Ordóñez, Trosky Alay; Córdova López, Patricio Fernando
Cognitive impairment is one of the most common problems in institutionalized older adults that affects quality of life and interferes with daily activities. The objective of this research was to determine the prevalence of cognitive impairment and associated risk factors in older adults at “Hogar Cristo Rey” of Cuenca city. An analytical and cross-sectional study was carried out, in 87 older adults, applying a data collection form and Mini-Mental Test (MMSE). The data obtained were transcribed and analyzed in SPSS 25, Epi Info 7.2.6.0 and Microsoft Excel 2019 statistical programs, and interpreted using percentages, frequencies, chi-square and odds ratio with CI95%. As results, the prevalence of cognitive impairment was 66.67%, the most frequent comorbidities were arterial hypertension, depression and diabetes mellitus II, in addition, statistically significant association (p<0.05) was found between cognitive impairment and the factors gender, polypharmacy and physical activity; the risk factors were female gender (OR 4.061; CI95% 1.580 - 10.440), the latter in the presence of mild impairment (OR 4.061; CI95% 1.580 - 10.440) and polypharmacy (OR 3.301; CI95% 1.293 - 8.425), the protective factor was physical activity in severe impairment (OR 0.164; CI95% 0.031 - 0.867). The prevalence of cognitive impairment in older adults at “Hogar Cristo Rey” is considerable, which evidences the presence of this condition in institutionalized people, also association was found with gender, polypharmacy and physical activity.
Prevalencia y factores de riesgo de epilepsia en el Hospital de Especialidades José Carrasco Arteaga, 2015-2020, Cuenca –Ecuador
(Universidad de Cuenca, 2022-09-08) Ulloa Bravo, Jimmy Santiago; Ulloa Dumas, Ana Victoria; Córdova López, Patricio Fernando
Background It is estimated that there are 50 million people with epilepsy. In Ecuador, the prevalence varies between 17-22/1,000. Risk factors are: family history, trauma, tumors, central nervous system infections, cerebrovascular events, etc. General Objective To determine the prevalence and risk factors for epilepsy at “Hospital de Especialidades José Carrasco Arteaga” in the years 2015-2020, Cuenca - Ecuador. Methods This research was an analytical, cross-sectional and prevalence study. The universe was the anonymous patient records of Hospital José Carrasco, 2015-2020. The sample was 382 records. The study variables were: epilepsy, age/sex, type of seizure, history: family, infections and tumors of the nervous system, head injuries, cerebrovascular events, neurodegenerative disease, immunosuppression. Frequency/percentages, chi square, odds ratio with its confidence interval (95%) were used. SPSS v21, Spanish, was used. Results The prevalence of epilepsy in adults was 10.14%. 66% of seizures were generalized, 77.5% tonic-clonic, and 8.9% absences. Risk factors were: family history (OD 7.2 CI 2.1-25.1), neurocysticercosis (OD 6.9 CI 2.0-23.8), tumors (OD 3.87 CI 1.4-10.6), trauma (OD 3.6 CI 1.6-7.8), and age (20-39 years) (OD 2.14 CI 1.3-3.4). Conclusions The prevalence of epilepsy in neurology patients was 10.14%. The crises were mainly of generalized origin, tonic-clonic and absences. Family history and neurocysticercosis increased the risk 7 times, tumors and trauma 4 times, and age between 20-39 years 2 times.