Valores del antígeno prostático específico en adultos de 50 a 59 años de las parroquias urbanas de la ciudad de Cuenca. 2013

Abstract

Prostate Specific Antigen (SPA) is a glycoprotein secreted by the prostate epithelial cells that plays an important role in liquefaction of semen and the sperm motility. The total PSA remains at levels below 4ng/ml, higher levels are detected in prostatitis, benign prostatic hyperplasia, prostate cancer, so it is necessary to regularly monitor the total PSA.

This study is observational and descriptive whose objective is to determine the values of PSA by micro ELISA technique in adults aged 50-59 years and then relate the test positivity with risk factors:age, heredity, toxic addictions, socio-economic factors, infection and inflammation of the urinary tract, sexual activity and venereal disease in a sample of 279 patients belonging to 15 urban parishes of Cuenca city. The processing of the samples was performed at the Laboratory Diagnostic Center and Biomedical Research of the Faculty of Medicine at the University of Cuenca, in compliance with biosafety standards and quality control.

We found the following results: 4% of the patients had values above 3.99ng/ml. The largest percentage (10%) of positive cases is in the age of 58-59 years.

When comparing the positive cases the study variables is statistical significance (p≤ 0.05) in the following: a family history of prostate disease, physical activity, cigarette smoking, alcohol and inflammation of the urinary tract.

KEYWORDS: PROSTATE SPECIFIC ANTIGEN ANALYSIS: MIDDLE-AGED/AGED; ENZYME–LINKED INMUNOSORBENT ASSAY METHOD; PROSTATIC NEOPLASMS EPIDEMIOLOGY; PROSTATIC HYPERPLASIA EPIDEMIOLOGY, PROSTATITIS EPIDEMIOLOGY; URBAN ZONES; CUENCA-ECUADOR.