Valores del antígeno prostático específico en adultos de 70 a 80 años de las parroquias urbanas de la Ciudad de Cuenca, 2013

Abstract

Prostate-specific antigen (PSA ) is a glycoprotein secreted by prostate epithelial cells plays an important role in liquefaction of semen and the sperm motility, total PSA remains at levels below 4ng/ml , higher values detected in prostatitis, benign prostatic hyperplasia , prostate cancer , so it is necessary to regularly monitor the total PSA.

This study is observational and descriptive whose objective is to determine the values of PSA by micro ELISA technique in adults 40 to 80 years and relate the test positivity with risk factors: age, heredity, toxic addictions, factors socioeconomic, infection and inflammation of the urinary, sexual activity and venereal disease in a sample of 275 patients belonging to 15 urban parishes of the city of Cuenca. The processing of the samples was performed at the Laboratory Diagnosis Center for Biomedical Research and the Faculty of Medicine at the University of Cuenca in compliance with biosafety standards and quality control. .

We found the following results: 15% of the patients had values above 3.99ng/ml. The largest percentage (36 %) of positive cases is in the age of 80 years.

When comparing the positive cases the study variables is statistical significance (p< 0.05) in the following: a family history of prostate disease, cigarette addiction, inflammation of the urinary tract.

KEYWORDS: PROSTATE SPECIFIC ANTIGEN/ANALYSIS; ELDER, ELDERLY; ENZYME-LINKED IMMUNOSORBENT ASSAY / METHODS; PROSTATIC NEOPLASMS / EPIDEMIOLOGY; PROSTATIC HYPERPLASIA / EPIDEMIOLOGY; PROSTATITIS / EPIDEMIOLOGY; URBAN ZONES; CUENCA-ECUADOR