Valores del antígeno prostático específico en adultos de 60 a 69 años de las parroquias urbanas de la Ciudad de Cuenca, 2013

Abstract

The Specific Prostate Antigen (SPA) is a glycoprotein secreted by the prostate epithelial cells that plays an important role in liquefaction of semen and the sperm motility. The total PSA remains at levels below 4ng/ml, higher levels are detected in prostatitis, benign prostatic hyperplasia, prostate cancer, so it is necessary to monitor the total PSA regularly This is an observational and descriptive study. The objective is to determine the values of prostate specific antigen by ‘Micro ELISA’ technique in adults aged 60-69 years and then relate analytically the test positivity with risk factors such as age, heredity, toxic addictions, socio-economic factors, infection and inflammation of the urinary tract, sexual activity and venereal disease in a sample of 276 patients belonging to 15 urban parishes of Cuenca city. The processing of the samples was performed at the Diagnostic Center and Biomedical Research of the Faculty of Medicine at the University of Cuenca, in compliance with biosafety standards and quality control. It was found that a 7% of tested patients had values above 3.99ng/ml. The higher percentage of positive cases (13%) is in the age group ranging from 64-65 years. When comparing the positive cases with the study variables, it founds a statistical significance (p≤ 0.05) in a familiar history of prostate disease, inflammation and infection of the urinary tract