Nivel de conocimiento sobre interacciones alimento-medicamento y factores asociados en la población del cantón Cuenca, 2023

Abstract

Background: Food-drug interactions affect drug pharmacokinetics, drug release, absorption, distribution, metabolism or elimination in the human body. Objectives: To determine the level of knowledge about food-drug interactions and associated factors in the population of Cuenca, Ecuador 2022-2023. Method: Validated 12-question questionnaire. Cross-sectional analytical study. Participants: 442. Sample size: was calculated with the EPIDAD 4.2 program. Data analysis: Stata MP-64.exe was used. Inferential analysis: the chi-square test was used, considering a difference of p value < 0.05 as significant. Type of association: the ODSS ratio was calculated with its confidence interval, considering as a risk factor values greater than 1, protective factor results less than 1, indifferent if equal to 1. Results: The 43.67%, of the surveyed population, respond affirmatively about having knowledge about the interaction between foods. The 51.13% recognize that over-the-counter medications and medications prescribed by the physician do not interact with herbal remedies and supplements. The 73.08% state that they have been recommended to avoid alcohol intake with medications. The 84.4% personnel related to the health area have knowledge about these interactions. Conclusions: It is evident in questions E, I the participants present a low level of knowledge of 14.03% and4.98% respectively. Moderate knowledge in A 43.67%, B 51.13%, D 40.27%, F 47.29%, G 36.20%, H 52.71%, J 34.16%, K 31.67% and L 36.20%. In question D there is a high level of knowledge of 73.08%.