Periodontal disease and COVID-19: prognosis and potential pathways of association in their pathogenesis

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2023

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Objective: The objective of this narrative review is to determine if periodontal disease is a factor in the development of a poor prognosis for COVID-19. Method: A bibliographic search was conducted in PubMed, Virtual Health Library, Google Scholar, and in the databases of Science Direct, Scopus, Lilacs, Bireme, Scielo, and Web of Science, using the following keywords: "COVID-19," "SARS-CoV-2," and "periodontal diseases." Results: Fifty-six records were retrieved from the database searches. After screening, 39 articles were selected for study: 13 reviews, 2 case-control studies, 1 systematic review, 8 letters to the editor, 2 cohort studies, 1 thesis, 7 hypotheses, 1 short communication, 3 commentaries, and 1 scoping review. Discussion: Both periodontal disease and COVID-19 produce an inflammatory response. This immune response generates an over-production of inflammatory cytokines that can harm overall health. Conclusion: The mouth serves as the entryway for many microorganisms that can harm health in general, among them SARS-CoV-2. It is important to maintain good oral health to lower the inflammatory load present in periodontal disease, lessening the possibility of complications from COVID-19.

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SARS-CoV 2

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http://dspace.ucuenca.edu.ec/handle/123456789/41711
 https://www.scopus.com/record/display.uri?eid=2-s2.0-85151043042&origin=resultslist&sort=plf-f&src=s&sid=09b38ff8a26435635966ac36bb10afea&sot=b&sdt=b&s=TITLE-ABS-KEY%28Periodontal+disease+and+COVID-19%3A+Prognosis+and+potential+pathways+of+association+in+their+pathogenesis%29&sl=118&sessionSearchId=09b38ff8a26435635966ac36bb10afea

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