Frecuencia de anticuerpos antipéptido citrulinado cíclico y factor reumatoide en pacientes con artritis reumatoide del Hospital de Especialidades José Carrasco Arteaga en el año 2019

Abstract

Rheumatoid arthritis is an autoimmune disease that affects joints, causing progressive damage and motor disability if early diagnosis and treatment are not established. According to studies carried out Latin America, the prevalence of this disease fluctuates around 1% predominantly in adulthood. Originally, the rheumatoid factor was considered a diagnostic marker for this disease, however, in 2010, the American College of Rheumatologic and the European League Against Rheumatism included the detection of anti-cyclic citrullinated peptide as a second diagnostic test parameter. The general objective is, to determinate the frequency of anti-cyclic citrullinated peptide antibodies and rheumatic factor in patients with rheumatoid arthritis at José Carrasco Arteaga Hospital in 2019. This is a descriptive cross-sectional study. Data were collected through a questionnaire, and they were interpreted through simple and cross tabulation featuring percentages and frequencies. The tabulation of the statistical data was carried out using the INM SPSS and Microsoft Excel software. The results were, the frequency of anti CCP antibodies and FR in total sample of 543 patients with rheumatoid arthritis was 69.24% and 88.77%. respectively. The age group with the highest number of cases ranged from 50 to 59 years (28%), from which the female population represented 80.85%. The majority of patients came from the rural area, totaling 51.01%. The frequency of the FR antibody was higher compared to the anti CCP in patients with rheumatoid arthritis. These antibodies were detected in the female population predominantly and more frequently, in the adulthood.