Determinación de las inmunoglobulinas G y M en leche materna humana (calostro)

Abstract

Breast milk is the preferred food for the baby since it has the composition required for development, growing and protection against external agents to which it is exposed out of the sterile belly.

This study was mainly based on the measurement of the concentration of immunoglobulin G and M in the secretion of the first 5 days postpartum (colostrum), using radial immunodiffusion method in 15 women attending Clinic Foundation Humanitarian Crespo Pablo Jaramillo whose samples were processed in the laboratory of Biological Analysis, School of Pharmacy and Biochemistry, Faculty of Chemistry, University of Cuenca, who were previously informed and invited to participate freely and voluntarily in this research.

It was possible to obtain the concentration of Ig M, being the average value of the first 24 hours of 204.54 mg/dL and the fifth day gradually decreased to an average of 14.52 mg/dL, while the concentration of Ig G the average value of the first 24 hours is 51.41 mg/dL on the fifth day and decreases to an average of 5.43 mg/dL.

Consequently, colostrum is rich in immunoglobulins especially the G, A and M, decreasing rapidly in the first compared to the other, this is how the newborn infant receives via colostrum immunoglobulin a great contribution pre- produced by the mother, providing passive immunization to keep out external aggressors at least the first six months of life until its own immune system develops. That's why, every mother must reach a moral awareness of breastfeeding, knowing that this will prevent your baby suffering from multiple illnesses and even prevented 13% of infant mortality, due to deficiency of normal maturation of your system immune defense as stated by the WHO (World Health Organization).