Perfil de resistencia de uropatógenos aislados en pacientes adultos mayores con comorbilidades en el Hospital Homero Castanier Crespo en el período julio 2019-julio 2020

Abstract

Background: Urinary tract infections are the most frequent antimicrobial subsidiary processes in the elderly population. The indiscriminate use of antibiotics increases the risk of developing bacterial resistance.

Aim: To know the resistance profile of isolated uropathogens in elderly patients with comorbidities at the Homero Castanier Crespo Hospital in the period july 2019-july 2020.

Methodology: descriptive, cross-sectional, study of 97 positive urocultives of elderly patients, through date base, calculated by Charlson index. The data were analyzed in the SPSS v.15.0 program, descriptive statistics such as frequency, percentage, mean and standard deviation were used; and, for statistical significance, chi-squared.

Results: The most frequent germs isolated were Escherichia coli 69.1%, Klepsiella spp 10.3% and Enterobacter spp 8.2%. 72.7% of the samples presented antibiotic resistance. 15,5% of the cultures were extended spectrum B-lactamase (ESBL), 2,1% resistence to meticilin & 1% showed presence of Carbapenemase producing Klepsiella pneumoniae. The highest resistence percentage was peniciline with a 34%, followed by cephalosporines with 32% resistence and fluoroquinolones with 19.6%. Conclusions: ESBL producing strains are common in urine cultures, the most common uropathogen was Escherichia coli .A large percentage of urine cultures presented antibiotic resistance.