Valoración de tres protocolos anestésicos en base a constantes fisiológicas y evaluación de la profundidad de la sedación en conejos (Oryctolagus cuniculus)

Abstract

This investigation was carried out at the University of Cuenca aimed to evaluated changes in heart rate (HR), respiratory rate (RR), and temperature (T°) and the anesthetic depth in domestic rabbits subjected to three anesthesic protocols: ketamine + xylazine; ketamine + xylazine+ acepromazine; ketamine + xylazine + diazepam, comprising treatments one, two and three respectively. For this purpose, a population of 15 male individuals of the same breed, with similar weight and age, clinically healthy, from the same hatchery was randomly taken; forming groups of 5 individuals for each treatment. Premedication was performed with intramuscular ketamine (20mg/kg) to facilitate the establishment of the endovenous route. The drugs were administered in slow infusion and physiological parameters were evaluated every 10 minutes and sedation depth every 15 minutes for one hour. The results in heart rate, respiratory rate and temperature showed that there is statistical significance (p<0.05) between the treatments evaluated, with T3 being the most promising treatment according to its performance in the experiment. As for anesthetic depth, it was evident that in general all the protocols used in this experiment proved to have a good anesthetic depth, so there is no difference between the use of any protocol evaluated here. In conclusion, the T3 treatment was the best in terms of the analysis of physiological constants and also showed a good anesthetic depth making it the most recommended treatment for anesthesia in this species.